Results 61 to 70 of about 175,846 (341)

Constraints on the Size and Composition of the Ancient Martian Atmosphere from Coupled CO2-N2-Ar Isotopic Evolution Models [PDF]

arXiv, 2023
Present-day Mars is cold and dry, but mineralogical and morphological evidence shows that liquid-water existed on the surface of ancient Mars. In order to explain this evidence and assess ancient Mars's habitability, one must understand the size and composition of the ancient atmosphere.
arxiv  

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

SO₂ noontime-peak phenomenon in the North China Plain [PDF]

Atmospheric Chemistry and Physics, 2014
A phenomenon of frequent noontime SO2 concentration peaks was discovered in a detailed analysis of the SO2 concentrations in the North China Plain (NCP). The possible causes and their contributions are analyzed.
W. Y. Xu, C. S. Zhao, L. Ran, W. L. Lin, P. Yan, X. B. Xu   +5 more
doaj   +1 more source

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

FEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya, Ksenia V. Sergeeva, Boris S. Shenkman, Timur M. Mirzoev   +3 more
wiley   +1 more source

Light-absorption of dust and elemental carbon in snow in the Indian Himalayas and the Finnish Arctic [PDF]

Atmospheric Measurement Techniques, 2018
Light-absorbing impurities (LAIs) deposited in snow have the potential to substantially affect the snow radiation budget, with subsequent implications for snow melt.
J. Svensson, J. Ström, N. Kivekäs, N. B. Dkhar, N. B. Dkhar, S. Tayal, S. Tayal, V. P. Sharma, V. P. Sharma, A. Jutila, A. Jutila, J. Backman, A. Virkkula, M. Ruppel, A. Hyvärinen, A. Hyvärinen, A. Kontu, H.-R. Hannula, M. Leppäranta, R. K. Hooda, R. K. Hooda, A. Korhola, E. Asmi, H. Lihavainen   +23 more
doaj   +1 more source

Effects of Bulk Composition on The Atmospheric Dynamics on Close-in Exoplanets [PDF]

, 2016
Super Earths and mini Neptunes likely have a wide range of atmospheric compositions, ranging from low-molecular mass atmospheres of H2 to higher molecular atmospheres of water, CO2, N2, or other species. Here, we systematically investigate the effects of atmospheric bulk compositions on temperature and wind distributions for tidally locked sub-Jupiter ...
arxiv   +1 more source

Atmospheres as a Window to Rocky Exoplanet Surfaces [PDF]

arXiv, 2023
As the characterization of exoplanet atmospheres proceeds, providing insights into atmospheric chemistry and composition, a key question is how much deeper into the planet we might be able to see from its atmospheric properties alone. For small planets with modest atmospheres and equilibrium temperatures, the first layer below the atmosphere will be ...
arxiv  

Positive feedback loop between MAPK and aquaporin 7 regulates autophagy and apoptosis induced by palmitate in RIN‐m5f cells

FEBS Open Bio, EarlyView.
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang, Jiang Tan, Xueting He, Yuqin Chen, Guoping Qiu, Mei Yang   +5 more
wiley   +1 more source

Effects of ship emissions on air quality in the Baltic Sea region simulated with three different chemistry transport models [PDF]

Atmospheric Chemistry and Physics, 2019
The Baltic Sea is a highly frequented shipping area with busy shipping lanes close to densely populated regions. Exhaust emissions from ship traffic into the atmosphere do not only enhance air pollution, they also affect the Baltic Sea environment ...
M. Karl, J. E. Jonson, A. Uppstu, A. Aulinger, M. Prank, M. Prank, M. Sofiev, J.-P. Jalkanen, L. Johansson, M. Quante, V. Matthias   +10 more
doaj   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source