Results 71 to 80 of about 3,727,608 (358)
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
FEBS Letters, EarlyView.TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling +4 more
wiley +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Effects of ship emissions on air quality in the Baltic Sea region simulated with three different chemistry transport models [PDF]
Atmospheric Chemistry and Physics, 2019 The Baltic Sea is a highly frequented shipping area with busy shipping lanes close to densely populated regions. Exhaust emissions from ship traffic into the atmosphere do not only enhance air pollution, they also affect the Baltic Sea environment ...
M. Karl +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
SO2 noontime-peak phenomenon in the North China Plain [PDF]
Atmospheric Chemistry and Physics, 2014 A phenomenon of frequent noontime SO2 concentration peaks was discovered in a detailed analysis of the SO2 concentrations in the North China Plain (NCP). The possible causes and their contributions are analyzed.
W. Y. Xu +5 more
doaj +1 more source
Frontiers in Environmental Science, 2022 Located in East Asia, the North China Plain (NCP) has a severe air pollution problem. In this study, variations in visibility, particulate matter (PM), gaseous pollutants, vertical meteorological parameters, and different types of aerosols and their ...
Hujia Zhao +12 more
doaj +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
, 2015 This article presents the In-service Aircraft of a Global Observing System (IAGOS) developed for operations on commercial long-range Airbus aircraft (A330/A340) for monitoring the atmospheric composition.
P. Nédélec +8 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Aerosol and Air Quality Research, 2021 Nanoparticles are a topic of interest because of their effects on human health and the climate, but the current options for evaluating their chemical composition—one of the key properties that determine the mechanisms of these effects—remain very limited
Sampsa Martikainen +5 more
doaj +1 more source