Results 61 to 70 of about 744,956 (222)

Acoustic optimisation and prediction of sound propagation in turbofan engine ducts

, 2010
The research presented in this thesis explores the prediction of noise propagation andradiation in turbofan engine intakes and bypass ducts, and the optimisation of noise attenuationby using acoustic liners.
Achunche, Iansteel Mukum
core   +1 more source

USP4‐Dependent CHAF1B Stabilization Regulates Distinct SETDB1 Ubiquitin States Linked to AKT T308 Signaling and Lipogenic Remodeling in HCC

Advanced Science, EarlyView.
USP4 stabilizes CHAF1B by limiting K48‐linked ubiquitination. Stabilized CHAF1B supports UHRF1‐associated K63‐linked SETDB1 ubiquitination and cytoplasmic redistribution, whereas CHAF1B loss favors VHL‐dependent K11‐associated degradative ubiquitination and proteasomal loss of SETDB1.
Saiyan Bian, Yun Tong, Wenkai Ni, Zhangzhi Tang, Weiting Chen, Kexin Ma, Lihan Jiang, Jiayu Shao, Xuyang He, Wenjie Zheng   +9 more
wiley   +1 more source

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

Advanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin, Jiani Li, Panqin Ma, Shinan Wu, Wenying Guan, Yimin Huang, Ke Feng, Mingyan Wei, Zixuan Yang, Shujia Guo, Caihong Huang, Yun‐Long Wu, Yi Han, Zuguo Liu   +13 more
wiley   +1 more source

ZMIZ2–DUX4–LGR5 Signaling Axis Maintains Stemness Properties and Facilitates Docetaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study identifies ZMIZ2 as a therapeutic target for docetaxel‐resistant triple‐negative breast cancer, sustaining cancer stemness‐associated properties and docetaxel resistance. ZMIZ2 upregulation enhances DUX4‐mediated LGR5 activation through the SWI/SNF components BRG1 and BAF57.
Xueting Gan, Shulei Sun, Ran Hu, Yuheng Feng, Xinhao Wu, Fangqi Liu, Xuyong Lin, Xiupeng Zhang, Xuezhu Rong, Qiang Han   +9 more
wiley   +1 more source

The Characteristics of Tumor Microenvironment by the Single Cell Profile in Endometrial Cancer of no Specific Molecular Profile (NSMP) Subtype

Advanced Science, EarlyView.
A subset of tumor‐associated macrophages (TAMs) characterized by SPP1 expression is discovered, which may remodel the tumor microenvironment by potentially promoting CD4+ T cell stress and maintaining epithelial cell stemness through SPP1‐CD44, thereby potentially contributing to the proliferation and migration of tumor cells, which has been verified ...
Xinhui Yuan, Zhengyao Zhai, Chuyu Jing, Wei Zhang, Wenjuan Tian, Yulan Ren   +5 more
wiley   +1 more source

University of Arizona, Institute of Atmospheric Physics, Progress Report No. 3

, 1956
This title from the Institute of Atmospheric Physics Reports collection is made available by the Department of Hydrology & Atmospheric Sciences and the University Libraries, University of Arizona.
Braham, Roscoe R., Jr.
core   +3 more sources

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

Advanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan, Haoming Shu, Rui Gao, Yilong Ren, Wu Ye, Xuhui Ge, Yao Gu, Yufeng Zhu, Xiaokun Wang, Honglin Teng, Xuhui Zhou, Wei Liu, Yang Gao, Jianquan Zhao, Weihua Cai   +14 more
wiley   +1 more source

University of Arizona, Institute of Atmospheric Physics, Progress Report No. 2

, 1955
This title from the Institute of Atmospheric Physics Reports collection is made available by the Department of Hydrology & Atmospheric Sciences and the University Libraries, University of Arizona.
Braham, Roscoe R., Jr.
core   +3 more sources

Human Excreta as a Stable and Important Source of Atmospheric Ammonia in the Megacity of Shanghai.

PLoS ONE, 2015
Although human excreta as a NH3 source has been recognized globally, this source has never been quantitatively determined in cities, hampering efforts to fully assess the causes of urban air pollution.
Yunhua Chang, Congrui Deng, Anthony J Dore, Guoshun Zhuang   +3 more
doaj   +1 more source

Applicability of condensation particle counters to measure atmospheric clusters [PDF]

, 2008
This study presents an evaluation of a pulse height condensation particle counter (PH-CPC) and an expansion condensation particle counter (E-CPC) in terms of measuring ambient and laboratory-generated molecular and ion clusters. Ambient molecular cluster
O'Dowd, Colin D., Curtius, Joachim, A. Kürten, Petäjä, Tuukka, Petäjä, T., Vartiainen, E., Manninen, Hanna Elina, Riipinen, Ilona, I. Riipinen, Junninen, H., E. Asmi, M. Kulmala, Kürten, A., Riipinen, I., Manninen, H. E., H. E. Manninen, S. Borrmann, Vartianinen, E., Sipilä, Mikko, K. Lehtipalo, Kürten, Christoph Andreas, M. Sipilä, Lehtipalo, Katrianne, Aalto, Pasi, E.-M. Kyrö, Kyrö, Ella-Maria, Asmi, E., Kyrö, E.-M., Borrmann, Stephan, Curtius, J., Sipilä, M., Kulmala, M., H. Junninen, J. Curtius, Aalto, P. P., Borrmann, S., Junninen, Heikki, O'Dowd, C. D., Asmi, Eija, P. P. Aalto, C. D. O'Dowd, Lehtipalo, K., T. Petäjä, Kulmala, Markku   +43 more
core   +2 more sources