Results 71 to 80 of about 15,535 (284)

An Oxidation Gradient Straddling the Small Planet Radius Valley

The Astrophysical Journal
We present a population-level view of volatile gas species (H _2 , He, H _2 O, O _2 , CO, CO _2 , CH _4 ) distribution during the sub-Neptune to rocky planet transition, revealing in detail the dynamic nature of small planet atmospheric compositions. Our
Collin Cherubim, Robin Wordsworth, Dan J. Bower, Paolo A. Sossi, Danica Adams, Renyu Hu   +5 more
doaj   +1 more source

O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer

Advanced Science, EarlyView.
This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu, Xueting Ren, Zhen Zhai, Lu Wang, Liang Liang, Zengqi Tan, Jiazhen Zhao, Yuxuan Han, Yuhan Li, Feng Guan, Xiang Li   +10 more
wiley   +1 more source

The First Dedicated Survey of Atmospheric Escape from Planets Orbiting F Stars

The Astronomical Journal
Hydrodynamic escape can strip the envelopes of close-in exoplanets, but most observations of atmospheric mass loss to date have been confined to planets orbiting K and M dwarfs.
Morgan Saidel, Shreyas Vissapragada, Heather A. Knutson, Ethan Schreyer, Michael Greklek-McKeon, Jonathan Gomez Barrientos, W. Garrett Levine, Carlos Gascón, George W. King, Morgan MacLeod, Haedam Im, Nick Tusay   +11 more
doaj   +1 more source

Martian atmosphere sputtering escape generated by penetrating hydrogen energetic neutral atoms

Earth and Planetary Physics
Atmospheric escape plays a critical role in shaping the long-term climate evolution of Mars. Among the various escape mechanisms, energetic neutral atoms (ENAs) generated through charge exchange between solar wind ions and exospheric neutrals serve as an
JiJie Ma, LingGao Kong, Hao Gu, WenYa Li, YuMing Wang, YuTian Chi, BinBin Tang, XiaoPeng Liu, YiFan Song, BaiQu Pu, FuHao Qiao, LiMin Wang, Jun Cui, Yong Wei, AiBing Zhang, Chi Wang   +15 more
doaj   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

Far-ultraviolet Flares and Variability of the Young M Dwarf AU Mic: A Nondetection of Planet C in Transit at Lyα

The Astronomical Journal
Atmospheric escape’s potential to shape the exoplanet population motivates detailed observations of systems actively undergoing escape. AU Mic is a young and active M dwarf hosting two close-in transiting sub- to Neptune-sized planets. Atmospheric escape
Keighley E. Rockcliffe, Elisabeth R. Newton, Allison Youngblood, Girish M. Duvvuri, Emily A. Gilbert, Peter Plavchan, Peter Gao, Hans-R. Müller, Adina D. Feinstein, Thomas Barclay, Eric D. Lopez   +10 more
doaj   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Oxygen Left Behind: Atmospheric Enrichment Due to Fractionation in Sub-Neptunes Using BOREAS

The Astrophysical Journal
The evolution of exoplanetary atmospheres is strongly influenced by atmospheric escape, particularly for close-in planets. Fractionation during atmospheric loss can preferentially remove lighter elements such as hydrogen, while retaining heavier species ...
Marilina Valatsou, Caroline Dorn, Pierlou Marty, James E. Owen   +3 more
doaj   +1 more source

The impacts of coronal mass ejections on the space environments of Venus and Mars

地球与行星物理论评
Coronal mass ejections (CME) are solar transients, and their impacts on the planets within the solar system have attracted considerable attention. As neighboring planets within the solar system, Venus and Mars are also directly and indirectly affected by
Qi Xu, Lianghai Xie, Lei Li, Xiaojun Xu
doaj   +1 more source

Note on Inquiries as to the Escape of Gases from Atmospheres [PDF]

The Astrophysical Journal, 1900
Abstract We have now three investigations which profess to supply information about the escape of gases from atmospheres. Two of them, those of Messrs. Cook and Bryan, reason forward by the help of the kinetic theory of gas from the supposed causes; the third, which is that preferred by the present writer, reasons backward by the help
openaire   +1 more source