Results 81 to 90 of about 15,535 (284)

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

open access: yesAdvanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi   +13 more
wiley   +1 more source

Helium Depletion in Escaping Atmospheres of Sub-Neptunes: A Signature of Primary-to-secondary Transition

open access: yesThe Astrophysical Journal
Short-period sub-Neptunes are common in extrasolar systems. These sub-Neptunes are generally thought to have primary atmospheres of protoplanetary-disk gas origin.
Issei Kobayashi   +3 more
doaj   +1 more source

The response of exospheric neutral hydrogen to weak geomagnetic disturbances between June 12 and 29, 2008

open access: yesFrontiers in Astronomy and Space Sciences
Stereoscopic remote sensing observations of terrestrial far ultraviolet (Lyman-α at 121.6 nm) emissions at solar minimum have been used to retrieve the time-dependent response of the exospheric 3-D neutral hydrogen (H) density at radial distances of 3–6 ...
Jochen H. Zoennchen   +2 more
doaj   +1 more source

Efficient metal emissions in the upper atmospheres of close-in exoplanets

open access: yesEarth and Planetary Physics, 2018
Atmospheric escape is a key process controlling the long term evolution of planets. Radiative cooling competes for energy against atmospheric escape in planetary upper atmospheres.
Lei Liu, Feng Tian
doaj   +1 more source

Escape of atmospheric gases from the Moon

open access: yesJournal of Earth System Science, 2005
The escape rate of atmospheric molecules on the Moon is calculated. Based on the assumption that the rates of emission and escape of gases attain equilibrium, the ratio of molecular number densities during day and night, n0d/n0n, can be explained.
Da Dao-an, Yang Ya-tian
openaire   +2 more sources

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang   +7 more
wiley   +1 more source

On the Divergent Evolution of Io and Europa as Primordial Ocean Worlds

open access: yesThe Astrophysical Journal
The Galilean moons exhibit a decrease in bulk density with distance from Jupiter, which may reflect differences in evolutionary paths and water loss. Early in its history, Jupiter was more luminous, which may have driven substantial atmospheric escape on
Yannis Bennacer   +2 more
doaj   +1 more source

Source codes for escape analysis

open access: yes, 2021
The source codes for atmospheric escape ...
Qin, Jianqi
core   +1 more source

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu   +17 more
wiley   +1 more source

Predictive analytics of cold ion outflow from the Earth’s ionosphere

open access: yesFrontiers in Astronomy and Space Sciences
In this study, we investigate the cold ions (<70 eV) originated in the high-latitude ionosphere of the Earth entering the magnetosphere towards the magnetotail.
Nicolas Doepke   +7 more
doaj   +1 more source

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