Results 41 to 50 of about 27,752,256 (308)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Observations and modeling of the boundary layer accompanying a tropical squall line [PDF]

, 1983
April 1983.Sponsored by the National Science Foundation, Division of Atmospheric Sciences ATM-8015347.Sponsored by the National Science Foundation, Division of Atmospheric Sciences ATM ...
Department of Atmospheric Science, Colorado State University, publisher, Johnson, Richard H., author, Nicholls, Melville, author   +2 more
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Linear spectral model of tropical mesoscale systems [PDF]

, 1979
June, 1979.Sponsored by the Global Atmospheric Research Program, National Science Foundation and the GATE Project Office, NOAA ATM 77-15369.Sponsored by the Global Atmospheric Research Program, National Science Foundation and the GATE Project Office ...
Silva Dias, Maria Faus, author, Department of Atmospheric Science, Colorado State University, publisher   +1 more
core  

Five Mars Years of Cloud Observations at Gale Crater: Opacities, Variability, and Ice Crystal Habits

The Planetary Science Journal
We update the record of cloud opacity observations conducted by the Mars Science Laboratory (MSL) Curiosity rover to cover the first five Mars Years (MYs) of the mission ( L _s = 160° of MY 31 to L _s = 160° of MY 36).
Conor W. Hayes, Jacob L. Kloos, Alex C. Innanen, Charissa L. Campbell, Haley M. Sapers, John E. Moores   +5 more
doaj   +1 more source

Megathrust Earthquake Potential of the Manila Subduction Systems Revealed by the Radial Component of Seismic Moment Tensors Mrr

Terrestrial, Atmospheric and Oceanic Sciences, 2015
We undertook an investigation of the seismic behavior of large earthquake and estimated the crustal deformation state in the northern Philippine area in terms of the radial component of seismic moment tensors (Mrr) distribution.
Jing-Yi Lin, Wen-Nan Wu, and Chung-Liang Lo   +2 more
doaj   +1 more source

Lorenz Energy Cycle: Another Way to Understand the Atmospheric Circulation on Tidally Locked Terrestrial Planets

The Planetary Science Journal, 2023
In this study, we employ and modify the Lorenz energy cycle (LEC) framework as another way to understand the atmospheric circulation on tidally locked terrestrial planets. It well describes the atmospheric general circulation in the perspective of energy
Shuang Wang, Jun Yang
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Comparison between the measured and calculated spectral characteristics of shortwave radiation in the free atmosphere over the desert (from the data of the CAENEX-70 expeditions) [PDF]

, 1976
This contribution is one in a series of reports which will be published jointly as an Atmospheric science paper, from the Dept. of Atmospheric Science, Colorado State University, Fort Collins, and in the Transactions of the Main Geophysical Observatory ...
Department of Atmospheric Science, Colorado State University, publisher, Kondratyev, K. Ya, author   +1 more
core  

Inverse modeling of European CH4 emissions: sensitivity to the observational network [PDF]

, 2009
Inverse modeling is widely employed to provide “top-down” emission estimates using atmospheric measurements. Here, we analyze the dependence of derived CH4 emissions on the sampling frequency and density of the observational surface network, using the ...
Bergamaschi, P., Villani, M.G., Sub Atmospheric physics and chemistry, Krol, M., Krol, M.C., Dep Natuurkunde, Dentener, F., Villani, M. G., Marine and Atmospheric Research, Meirink, J.F.   +9 more
core   +2 more sources