Results 41 to 50 of about 28,891,464 (311)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Diagnostic tests of models for the thermal structure of the non-precipitating convective boundary layer [PDF]

, 1974
April 1974.Sponsored by National Science Foundation, Atmospheric Sciences Section GA-33182.Sponsored by National Science Foundation, Atmospheric Sciences Section GA ...
Department of Atmospheric Science, Colorado State University, publisher, Betts, Alan K., author, Moore, Douglas A., author   +2 more
core  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Observations and modeling of the boundary layer accompanying a tropical squall line [PDF]

, 1983
April 1983.Sponsored by the National Science Foundation, Division of Atmospheric Sciences ATM-8015347.Sponsored by the National Science Foundation, Division of Atmospheric Sciences ATM ...
Department of Atmospheric Science, Colorado State University, publisher, Johnson, Richard H., author, Nicholls, Melville, author   +2 more
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Design of an axisymmetric primitive equation tropical cyclone model [PDF]

, 1976
December 1976.Includes bibliographical references (pages 67-69).Sponsored by the Global Atmospheric Research Program, Climate Dynamics Research Section, National Science Foundation DES 74-11438.Sponsored by the Global Atmospheric Research Program ...
Department of Atmospheric Science, Colorado State University, publisher, Hack, James J., author, Schubert, Wayne H., author   +2 more
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Comparison between the measured and calculated spectral characteristics of shortwave radiation in the free atmosphere over the desert (from the data of the CAENEX-70 expeditions) [PDF]

, 1976
This contribution is one in a series of reports which will be published jointly as an Atmospheric science paper, from the Dept. of Atmospheric Science, Colorado State University, Fort Collins, and in the Transactions of the Main Geophysical Observatory ...
Department of Atmospheric Science, Colorado State University, publisher, Kondratyev, K. Ya, author   +1 more
core  

Measuring Micrometers of Matter and Inventing Indices: Entangling Social Perception within Discrete and Continuous Measurements of Air Quality

Social Sciences, 2019
Environmental protection agencies around the globe are establishing different methods for measuring particulates, and then integrating those measurements into a single air quality index with other pollutants. At the same time, scientific inquiry has also
Edwin Schmitt
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source