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Preface: 6th International Electronic Conference on Atmospheric Sciences

Environmental Sciences Proceedings
The sixth International Electronic Conference on Atmospheric Sciences, the range of topics will remain more general, but we are open to subject areas with a thematic topic of importance, especially interdisciplinary or transdisciplinary science [...]
Anthony R. Lupo
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

THE OVERVIEW OF THE PLANETARY ATMOSPHERIC SPECTRAL TELESCOPE (PAST) IN THE SCIENTIFIC EXPERIMENTAL SYSTEM IN NEAR-SPACE (SENSE) [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
To investigate mass transport and energy dissipation in space environments for solar system planet, a balloon-borne planetary atmospheric spectral telescope (PAST) is designed with 0.8-m aperture in spectral range from 280 nm to 680 nm will
Q. Meng, F. He, W. Zhao, K. Wang, L. Yang, J. Dong, X. Wang   +6 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Applications of airborne remote sensing in atmospheric sciences research [PDF]

, 1984
This paper explores the potential for airborne remote sensing for atmospheric sciences research. Passive and active techniques from the microwave to visible bands are discussed. It is concluded that technology has progressed sufficiently in several areas
Phillips, B. B., Serafin, R. J., Szejwach, G.   +2 more
core   +1 more source

Origin of atmospheric aerosols at the Pierre Auger Observatory using backward trajectory of air masses

, 2012
The Pierre Auger Observatory is the largest operating cosmic ray observatory ever built. Calorimetric measurements of extensive air showers induced by cosmic rays are performed with a fluorescence detector.
, Abreu P [Pierre Auger Collaboration], Fick B, GD Rolph, Karim Louedec, Louedec K, MI Micheletti, RR Draxler   +7 more
core   +3 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Atmospheric Sciences Grants

Eos, Transactions American Geophysical Union, 1982
The Division of Atmospheric Sciences in the National Science Foundation (NSF) is experimenting with a new system for grant renewal, according to Joan M. Jordon, special assistant to division director Eugene W. Bierly. The experimental system, based on a similar experiment by NSF's Division of Chemistry, aims to reduce rising costs and mounting ...
openaire   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source