Results 51 to 60 of about 5,065,100 (341)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Seasonal shifts in pan-Arctic Ocean downward radiation and key drivers

iScience
Summary: The Arctic, highly sensitive to climate change, is warming rapidly due to increasing greenhouse gas emissions, resulting in a significant rise in downward radiation over the pan-Arctic Ocean in recent decades.
Yujun Liu, Haiyan Li, Yijun He, Yingying Liu   +3 more
doaj   +1 more source

VIII ALL-RUSSIAN CONFERENCE ON ATMOSPHERIC ELECTRICITY [PDF]

Vestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2019
From September 23 to September 27, 2019, the VIII All-Russian Conference on Atmospheric Electricity was held in Nalchik. The conference was organized by the Russian Academy of Sciences, the A.F.
P.P. Firstov, V. I Kozlov, E. I. Malkin
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Land–atmosphere feedbacks exacerbate concurrent soil drought and atmospheric aridity

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Soil drought and atmospheric aridity can be disastrous for ecosystems and society. This study demonstrates the critical role of land–atmosphere feedbacks in driving cooccurring soil drought and atmospheric aridity.
Sha Zhou, Sha Zhou, A. P. Williams, A. Berg, B. Cook, B. Cook, Yao Zhang, S. Hagemann, R. Lorenz, S. Seneviratne, P. Gentine   +10 more
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

AERONET sun photometer as a didactic tool for understanding aerosol refractive index in the atmosphere: a case study for central Amazon [PDF]

Revista Brasileira de Ensino de Física
As the impacts of climate change become increasingly evident, understanding the role of atmospheric aerosols in regulating Earth’s climate is crucial. Despite their significance, the optical properties of aerosols remain unclear to the general public and,
Marco A. Franco, Pedro H.T. Tavares, Luciana V. Rizzo, Fernando G. Morais, Rafael Palácios, Paulo Artaxo   +5 more
doaj   +1 more source

Land–atmospheric feedbacks during droughts and heatwaves: state of the science and current challenges

Annals of the New York Academy of Sciences, 2018
Droughts and heatwaves cause agricultural loss, forest mortality, and drinking water scarcity, especially when they occur simultaneously as combined events.
D. Miralles, P. Gentine, S. Seneviratne, A. Teuling   +3 more
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Web portal on environmental sciences "ATMOS'' [PDF]

Advances in Geosciences, 2006
The developed under INTAS grant web portal ATMOS (http://atmos.iao.ru and http://atmos.scert.ru) makes available to the international research community, environmental managers, and the interested public, a bilingual information source for the domain of
E. P. Gordov, V. N. Lykosov, A. Z. Fazliev   +2 more
doaj