Results 71 to 80 of about 5,065,100 (341)

The INSU and DMN network of ST radars [PDF]

open access: yes, 1986
Due to their capabilities of measuring wind profiles with good time and height resolution, Stratosphere-Troposphere (ST) are well adapted to carry out atmospheric research.
Baudin, F.   +5 more
core   +1 more source

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

open access: yesFEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu   +8 more
wiley   +1 more source

Interpreting contemporary trends in atmospheric methane

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Atmospheric methane plays a major role in controlling climate, yet contemporary methane trends (1982–2017) have defied explanation with numerous, often conflicting, hypotheses proposed in the literature.
A. Turner, C. Frankenberg, E. Kort
semanticscholar   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

Decadal Changes in the Linkage Between Autumn Sea Ice and the Winter Eurasian Temperature in the 20th Century

open access: yesGeophysical Research Letters, 2023
The Warm Arctic‐Cold Eurasia pattern in recent decades has attracted extensive attention and has been partly attributed to rapid sea‐ice loss; however, such a link has been unstable over the past century. Here, we use centennial reanalyzes to investigate
Xulong He   +4 more
doaj   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

Facilities for meteorological research at NASA Goddard/Wallops Flight Facility [PDF]

open access: yes
The technical characteristics of the Atmospheric Sciences Research Facility, the improvements being made to the instrumentation there which will enhance its usefulness in atmospheric research, and several of the on-going research programs are described ...
Carr, R. E., Gerlach, J. C.
core   +1 more source

High resolution spectroscopy in the microwave and far infrared [PDF]

open access: yes, 1990
High resolution rotational spectroscopy has long been central to remote sensing techniques in atmospheric sciences and astronomy. As such, laboratory measurements must supply the required data to make direct interpretation of data for instruments which ...
Pickett, Herbert M.
core   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

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