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Bahía Culebra se locoaliza en la parte norte de la costa Pacífica de Costa Rica. Es una región de afloramiento estacional, rica en ambientes y organismos marinos, y además, la zona de mayor desarrollo turístico del país. En este trabajo compilo y analizo
Jorge Cortés
doaj
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Preface: 6th International Electronic Conference on Atmospheric Sciences
The sixth International Electronic Conference on Atmospheric Sciences, the range of topics will remain more general, but we are open to subject areas with a thematic topic of importance, especially interdisciplinary or transdisciplinary science [...]
Anthony R. Lupo
doaj +1 more source
Grand challenges in atmospheric science [PDF]
As a subject of study, the atmospheric sciences encompass all the processes that occur in the atmosphere, together with its links with other systems, mainly the hydrosphere, cryosphere, lithosphere, biosphere, and outer space. As such it is an extensive discipline and the task of describing the main challenges is not an easy one, and entails a fair ...
openaire +2 more sources
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková+14 more
wiley +1 more source
Atmospheres of science: Experiencing scientific mobility [PDF]
This article uses notions of the atmospheric to engage with empirical material concerned with international mobility in science. It draws on recent conceptual work on atmospheres that frames them as allowing access to the affective qualities of everyday life and as ‘productively nebulous’: atmospheres exist between the local and the globally diffuse ...
openaire +5 more sources
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez+5 more
wiley +1 more source
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella+18 more
wiley +1 more source
Applications of airborne remote sensing in atmospheric sciences research [PDF]
This paper explores the potential for airborne remote sensing for atmospheric sciences research. Passive and active techniques from the microwave to visible bands are discussed. It is concluded that technology has progressed sufficiently in several areas
Phillips, B. B.+2 more
core +1 more source
Interpreting contemporary trends in atmospheric methane
Atmospheric methane plays a major role in controlling climate, yet contemporary methane trends (1982–2017) have defied explanation with numerous, often conflicting, hypotheses proposed in the literature.
A. Turner, C. Frankenberg, E. Kort
semanticscholar +1 more source