Results 31 to 40 of about 169,661 (317)

Effects of high-latitude atmospheric gravity wave disturbances on artificial HF radar backscatter [PDF]

, 2006
International audienceObservations of HF radar backscatter from artificial field-aligned irregularities in an ionosphere perturbed by travelling disturbances due to atmospheric gravity waves are presented.
Tim K. Yeoman (7583066), A. Senior, M. J. Kosch (7595327), I. W. McCrea, M. T. Rietveld (7594184), Rietveld, M. T., Senior, A., T. K. Yeoman, I. W. McCrea (7594871), M. T. Rietveld, Kosch, M. J., M. J. Kosch, A. Senior (3255282), McCrea, I. W., Yeoman, T. K.   +14 more
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A global coupled Eulerian-Lagrangian model and 1 × 1 km CO2 surface flux dataset for high-resolution atmospheric CO2 transport simulations [PDF]

, 2012
We designed a method to simulate atmospheric CO2 concentrations at several continuous observation sites around the globe using surface fluxes at a very high spatial resolution.
Lukyanov, A, M. Rigby, Nisbet, Euan, Maksyutov, S., Tsuboi, K, Lowry, David, A. Lukyanov, Matsueda, H, A. Varlagin, Andres, R. J., Fisher, R. E., Nisbet, E., Sawa, Y., V. Valsala, Saito, M, Nisbet, EG, Lukyanov, A., Varlagin, A, Nisbet, E. G., Oda, T, T. Oda, Maksyutov, S, Valsala, V, Andres, R.J., Varlagin, A., R. Toumi, H. Matsueda, R. Zhuravlev, Fisher, R., Toumi, R, Oda, T., Fisher, RE, Ganshin, A., Sawa, Y, Toumi, R., E. G. Nisbet, Lowry, D, Andres, R., Tsuboi, K., R. E. Fisher, R. J. Andres, Rigby, M, Rigby, M., S. Maksyutov, A. Ganshin, M. Saito, Lowry, D., Zhuravlev, R, D. Lowry, K. Tsuboi, Fisher, Rebecca, Matsueda, H., Y. Sawa, Valsala, V., Zhuravlev, R., Ganshin, A, Saito, M., Andres, RJ   +57 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A Survey of Structure of Atmospheric Turbulence in Atmosphere and Related Turbulent Effects [PDF]

, 2021
The Earth’s atmosphere is the living environment in which we live and cannot escape. Atmospheric turbulence is a typical random inhomogeneous medium, which causes random fluctuations of both the amplitude and phase of optical wave propagating through it.
Fazhi Wang, Qi Yuan, Daosen Liu, Shuang Feng, Wenhe Du   +4 more
core   +1 more source

The Silent Expansion of Fire Activity in Continental Tropical Asia shaped by natural and anthropogenic forces

Nature Communications
While research has largely focused on boreal fires, here we show a significant increase in spring fire activity across continental tropical Asia between 2001 and 2020, characterized by two prominent hotspots.
Qingyu Cai, Wen Chen, Yan Yu, Shangfeng Chen, Tianjiao Ma, Xu Xue, Jinling Piao   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The Diffusion Limit of Photoevaporation in Primordial Planetary Atmospheres

The Astrophysical Journal
Photoevaporation is thought to play an important role in early planetary evolution. In this study, we investigate the diffusion limit of X-ray- and ultraviolet-induced photoevaporation in primordial atmospheres.
Darius Modirrousta-Galian, Jun Korenaga
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Atmospheric circulation systems : their structure and physical interpretation / [PDF]

, 1969
Atmospheric circulation systems: their structure and physical interpretation.Includes bibliographical references and index.Front Cover; Atmospheric Circulation Systems: Their Structure and Physical Interpretation; Copyright Page; Preface; Contents; List ...
Palmén, E.(Erik),1898-1985., Newton, C. W.   +1 more
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