Results 51 to 60 of about 8,095,887 (293)
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Structure of the lower atmosphere of Venus
Abstract If the centimeter microwave emission from Venus arises from its surface, the radar reflectivities and microwave brightness temperatures give mean darkside surface temperatures of about 640° K. Extrapolations of the phase data to small phase angles indicate mean brightside surface temperatures of about 750° K.
openaire +2 more sources
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Thermoelastic Contraction as a Suppressor of Atmospheric Escape in Close-in Exoplanets
The survival of volatile-rich atmospheres on close-in exoplanets challenges classical escape models. We identify a fully classical, interior-driven correction: thermoelastic contraction of the planetary mantle slightly increases the gravitational binding
L. Yıldız, D. Kaykı, E. Güdekli
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
The Huygens Atmospheric Structure Instrument (HASI) is a multi-sensor package which has been designed to measure the physical quantities characterising the atmosphere of Titan during the Huygens probe descent on Titan and at the surface. HASI sensors are
Hamelin, Michel +90 more
core +2 more sources
Atmospheric compositions of sub-Neptunes and super-Earths are often interpreted as tracers of formation location relative to volatile ice lines. However, prolonged magma oceans can chemically equilibrate with primordial atmospheres and modify accreted ...
Aaron Werlen +4 more
doaj +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi +6 more
wiley +1 more source
Atmospheric circulation systems : their structure and physical interpretation /
Atmospheric circulation systems: their structure and physical interpretation.Includes bibliographical references and index.Front Cover; Atmospheric Circulation Systems: Their Structure and Physical Interpretation; Copyright Page; Preface; Contents; List ...
Palmén, E.(Erik),1898-1985. +1 more
core

