Results 61 to 70 of about 7,584,066 (287)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Planetary Waves Drive Horizontal Variations in Trace Species in the Venus Deep Atmosphere

The Planetary Science Journal
The deep atmosphere of Venus remains mysterious because of the planet’s high, optically thick cloud decks. While phenomena such as the observed decadal fluctuations in sulfur dioxide abundance above the clouds could shed light on conditions below, poor ...
Maureen Cohen, James Holmes, Stephen Lewis, Manish Patel   +3 more
doaj   +1 more source

Structure of the lower atmosphere of Venus

Icarus, 1962
Abstract If the centimeter microwave emission from Venus arises from its surface, the radar reflectivities and microwave brightness temperatures give mean darkside surface temperatures of about 640° K. Extrapolations of the phase data to small phase angles indicate mean brightside surface temperatures of about 750° K.
openaire   +2 more sources

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

High-resolution measurements of atmospheric molecular hydrogen and its isotopic composition at the West African coast of Mauritania [PDF]

, 2013
Oceans are a net source of molecular hydrogen (H-2) to the atmosphere, where nitrogen (N-2) fixation is assumed to be the main biological production pathway followed by photochemical production from organic material.
Kock, A, Sub Atmospheric physics and chemistry, A. Kock, Walter, S., S. Walter, T. Röckmann, Afd Marine and Atmospheric Research, Marine and Atmospheric Research, Kock, Annette, Röckmann, T.   +9 more
core   +3 more sources

Physician‐Scientist Pipeline for Pediatric Rheumatology: The Current Landscape and Future Perspectives

Arthritis Care &Research, EarlyView.
Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu, Linda T. Hiraki, Mara L. Becker   +2 more
wiley   +1 more source

Up, Up, and Away: Winds and Dynamical Structure as a Function of Altitude in the Ultrahot Jupiter WASP-76b

The Astrophysical Journal
Due to the unprecedented signal strengths offered by the newest high-resolution spectrographs on 10 m class telescopes, exploring the 3D nature of exoplanets is possible with an unprecedented level of precision.
Aurora Y. Kesseli, Hayley Beltz, Emily Rauscher, I. A. G. Snellen   +3 more
doaj   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source

Exploring atmospheric exchange with natural tracers [PDF]

, 2011
This study is focused on the application of radon (222Rn; half life time of 3.82 days) as an atmospheric tracer for evaluating the exchange of trace compounds between the land surface and the atmosphere and for understanding atmospheric mixing processes.
Xia, Yu
core   +1 more source