Results 91 to 100 of about 271,983 (269)
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Nursery habitats provide increased survival and growth and are a crucial early life-stage component for many fish and invertebrate populations. The biogenic structures that provide this nursery function, however, are increasingly degraded. Therefore, any
Andrew Martin Lohrer +5 more
doaj +1 more source
ESP3: An open-source software for the quantitative processing of hydro-acoustic data
ESP3 is an open-source software to process single-beam and split-beam echosounder data. Multiple displays, analysis tools parameterizable algorithms are available to the user to scrutinise their data, and a scripting module allows applying these to ...
Yoann Ladroit +3 more
doaj +1 more source
Made available in DSpace on 2016-11-14T22:36:28Z (GMT). No. of bitstreams: 2 ISWSIEM2001-02.pdf: 130966 bytes, checksum: 92fe4621bc81f3bd3f124d565db244e2 (MD5) license.txt: 3973 bytes, checksum: 6c1c5beee39794d995a5ff442f5bd9ab (MD5) Previous issue ...
Illinois State Water Survey
core
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Genetic connectivity studies can inform the design of mitigation strategies used in environmental management. However, the expense of developing species-specific molecular markers and collecting samples at appropriate spatial and temporal scales can be ...
Rachel Elizabeth Boschen +4 more
doaj +1 more source
Influences of the Indian Summer Monsoon on water vapour and ozone concentrations in the UTLS as simulated by Chemistry-Climate Models [PDF]
The representation of the Indian summer monsoon (ISM) circulation in some current chemistry–climate models (CCMs) is assessed. The main assessment focuses on the anticyclone that forms in the upper troposphere and lower stratosphere and the related ...
Garcia, R. +20 more
core +2 more sources
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur +5 more
wiley +1 more source
Comparison of an isotopic atmospheric general circulation model with new quasi-global satellite measurements of water vapor isotopologues [PDF]
We performed an intensive comparison of an isotope‐incorporated atmospheric general circulation model with vapor isotopologue ratio observation data by two quasi‐global satellite sensors in preparation for data assimilation of water isotope ratios.
Kanamitsu, Masao +18 more
core +1 more source
The corrosion performance of AlSi7Mg and AlSi10Mg alloys produced through selective laser melting (SLM) was examined under compressive stress in a chloride environment. Electrochemical analyses, including open‐circuit potential (OCP), potentiodynamic polarization (CPP), and electrochemical impedance spectroscopy (EIS), were complemented by scanning ...
Femi John Akinfolarin +2 more
wiley +1 more source

