Results 81 to 90 of about 271,983 (269)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

What causes the irregular cycle of the atmospheric tape recorder signal in HCN? [PDF]

, 2010
Variations in the mixing ratio of long-lived trace gases entering the stratosphere in the tropics are carried upward with the rising air with the signal being observable throughout the tropical lower stratosphere.
K. A. Walker, Müller, R., J.-U. Grooß, Riese, M., M. Riese, Grooss, J. -U., P. Konopka, Heil, A., Pumphrey, Hugh, R. Müller, Guenther, G., Grooß, J.-U., H.-C. Pumphrey, Schultz, M., A. Heil, Pommrich, R., Pumphrey, H.-C., Konopka, P., Walker, K. A., Walker, K.A., Günther, G., Mueller, R., G. Günther, R. Pommrich, M. Schultz   +24 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Twenty-six years of phytoplankton pigments reveal a circumpolar Class Divide around the Southern Ocean

Communications Earth & Environment
Regional taxonomic variation of phytoplankton communities in the Southern Ocean remains largely uncharacterised despite the distinct trophic and biogeochemical roles of different taxa in anthropogenic carbon uptake, biogeochemical processes, and as the ...
Alexander Hayward, Matthew H. Pinkerton, Simon W. Wright, Andrés Gutiérrez-Rodriguez, Cliff S. Law   +4 more
doaj   +1 more source

Simulation of Stratospheric Water Vapor Trends: Impact on Stratospheric Ozone Chemistry [PDF]

, 2004
A transient model simulation of the 40-year time period 1960 to 1999 with the coupled climate-chemistry model (CCM) ECHAM4.L39(DLR)/CHEM shows a stratospheric water vapor increase over the last two decades of 0.7 ppmv and, additionally, a short-term ...
Stenke, A., A. Stenke, V. Grewe, Grewe, V.   +3 more
core  

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Strontium as a tracer of weathering processes in a silicate catchment polluted by acid atmospheric inputs, Strengbach, France [PDF]

, 2000
This paper determines the weathering and atmospheric contributions of Ca in surface water from a small spruce forested silicate catchment (N–E France) receiving acid atmospheric inputs.
Aubert, Dominique, McNutt, R., B Fritz, A Probst, D Aubert, El Gh'mari, Abderrahmene, Probst, Anne, A El Gh'mari, Fritz, Bertrand, R McNutt   +9 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Simulating carbon exchange using a regional atmospheric model coupled to an advanced land-surface model [PDF]

, 2010
A large scale mismatch exists between our understanding and quantification of ecosystem atmosphere exchange of carbon dioxide at local scale and continental scales.
Hutjes, R.W.A., Maat, H.W., ter, Miglietta, F.   +2 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source