Results 61 to 70 of about 1,377,493 (242)

THz vs NIR laser-assisted atom probe tomography of LaB6 samples

open access: yesAPL Materials
Terahertz (THz) radiation with low-energy photons (meV) is used in a wide range of applications, such as microscopy, sensing, and spectroscopy. However, recently, high amplitude THz pulses of MV/cm have been generated and used for electron emission and ...
M. Karam   +4 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Atom-Scale Chemistry in Chalcopyrite-Based Photovoltaic Materials Visualized by Atom Probe Tomography

open access: yes, 2022
Chalcopyrite-based materials for photovoltaic devices tend to exhibit complex structural imperfections originating from their polycrystalline nature; nevertheless, properly controlled devices are surprisingly irrelevant to them in terms of resulting ...
Kanghoon Yim (5077382)   +14 more
core   +1 more source

Hierarchical nano-orderings enable extraordinary cryogenic strength-ductility synergy in a medium-entropy alloy

open access: yesNature Communications
Cryogenic alloys simultaneously achieving ultrahigh yield strength (YS ≥ 2.0 GPa) alongside substantial uniform elongation (UE) are critically needed, yet fundamentally constrained by the strength-ductility trade-off. Guided by Eshelby’s inclusion theory,
Dongdong Zhang   +11 more
doaj   +1 more source

Atom Probe Tomography of Aluminium Alloys: A Systematic Meta-Analysis Review of 2018

open access: yesMetals, 2019
Atom probe tomography (APT) is a microscopy technique that provides a unique combination of information, specifically the position and elemental identity of each atom in three dimensions.
Anna V. Ceguerra, Ross K.W. Marceau
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Atom probe tomography analysis of WC powder

open access: yes, 2013
A tantalum doped tungsten carbide powder, (W,Ta)C, was prepared with the purpose to maximise the amount of Ta in the hexagonal mixed crystal carbide. Atom probe tomography (APT) was considered to be the best technique to quantitatively measure the amount
Weidow, Jonathan,
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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