Results 71 to 80 of about 1,377,493 (242)

Nanoscale tomography reveals the deactivation of automotive copper-exchanged zeolite catalysts

Nature Communications, 2017
Cu-exchanged zeolite chabazite has superior stability over other catalysts in automotive NOx reduction. Here, the authors use atom probe tomography to create 3D nanoscale reconstructions of two Cu-containing zeolite catalysts, providing a complete ...
Joel E. Schmidt, Ramon Oord, Wei Guo, Jonathan D. Poplawsky, Bert M. Weckhuysen   +4 more
doaj   +1 more source

Field evaporation of germanium under THz pulses: application to atom probe tomography [PDF]

APL Materials
This study investigates the field evaporation behavior of germanium (Ge) under monocycle terahertz (THz) excitation using atom probe tomography (APT). The influence of THz pulse polarity, specimen geometry, and spectral content is systematically examined.
M. Karam, M. De Tullio, J. Houard, I. Blum, A. Vella   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Atomic-scale determination of surface facets in gold nanorods [PDF]

, 2012
It is widely accepted that the physical properties of nanostructures depend on the type of surface facets1, 2. For Au nanorods, the surface facets have a major influence on crucial effects such as reactivity and ligand adsorption and there has been ...
Van der Broek, Wouter, Carbó Argibay, Enrique, Carb\uf3-Argibay, Enrique, Liz-Marz\ue1n, Luis M., Goris, Bart, Liz Marzán, Luis, G\uf3mez-Gra\uf1a, Sergio, Van Tendeloo, Gustaaf, Bals, Sara, Gómez Graña, Sergio, van den Broek, Wouter   +10 more
core   +1 more source

Atomic-scale age resolution of planetary events

Nature Communications, 2017
Constraining the timing of crustal processes and impact events remains challenging. Here, the authors show that atom probe tomography can produce highly accurate U-Pb isotopic age constraints in baddeleyite crystals, which is a common phase in ...
L. F. White, J. R. Darling, D. E. Moser, D. A. Reinhard, T. J. Prosa, D. Bullen, D. Olson, D. J. Larson, D. Lawrence, I. Martin   +9 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Atom-probe tomography characterization of the oxidation of stainless steel

, 2010
Three-dimensional atomic characterization of oxidation in stainless steels under simulated nuclear reactor conditions has been achieved with atom-probe tomography (APT).
T. Yamada (7703801), T. Terachi (23303461), David Saxey (23290591), S. Lozano-Perez (23303458)   +3 more
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Atom probe tomography in nanoelectronics

, 2014
International audienceThe role of laser assisted atom probe tomography (APT) in microelectronics is discussed on the basis of various illustrations related to SiGe epitaxial layers, bipolar transistors or MOS nano-devices including gate all around (GAA ...
Didier Blavette, Sébastien Duguay, Duguay, Sébastien, Blavette, Didier   +3 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source