Results 111 to 120 of about 100,070 (278)

Accelerating the averaging rate of atomic ensemble clock stability using atomic phase lock

New Journal of Physics, 2014
We experimentally demonstrated that the stability of an atomic clock improves at its fastest rate τ ^−1 (where τ is the averaging time) when the phase of a local oscillator is genuinely compared to the continuous phase of many atoms in a single trap (an ...
Nobuyasu Shiga, Michiaki Mizuno, Kohta Kido, Piyaphat Phoonthong, Kunihiro Okada   +4 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Test of the gravitational redshift with single-photon-based atomic clock interferometers

Quantum Frontiers
The gravitational redshift (GR), as predicted by Einstein’s general theory of relativity, posits that two identical clocks situated at different gravitational potentials will tick at different rates.
Ju Liu, Yaoyao Xu, Huaqing Luo, Lushuai Cao, Minkang Zhou, Xiaochun Duan, Zhongkun Hu   +6 more
doaj   +1 more source

High-precision Frequency Drift Compensation Study of High-performance Rubidium Atomic Clock

Chinese Journal of Magnetic Resonance
With their high reliability, small size and low power consumption, rubidium atomic clocks are widely used in the fields of navigation, communication, etc. In particular, rubidium atomic clocks for navigation satellites have developed excellent stability.
XU Junqiu, LI Junyao, ZHAO Feng, KANG Songbai, Wang Pengfei, Ming Gang   +5 more
doaj   +1 more source

Geopotential determination based on a direct clock comparison using two-way satellite time and frequency transfer

Terrestrial, Atmospheric and Oceanic Sciences, 2019
According to Einstein’s general relativity theory, a precise (atomic) clock runs faster at a position with higher gravitational potential than a clock at a position with lower potential.
Wen-Bin Shen, Xiao Sun, Chenghui Cai, Kuangchao Wu, Ziyu Shen   +4 more
doaj   +1 more source

Lindblad decoherence in atomic clocks

Physical Review A, 2016
It is shown how possible corrections to ordinary quantum mechanics described by the Lindblad equation might be detected by exploiting the great precision of atomic clocks.
openaire   +3 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Enhancing Optical Lattice Clock Coherence Times with Erasure Conversion

PRX Quantum
Increasing coherent interrogation times is central to advancing the precision of optical clocks. Synchronous differential optical clock comparisons have now demonstrated atomic coherence times that far exceed the coherence time of the clock laser.
Shuo Ma, Jonathan Dolde, Xin Zheng, Dhruva Ganapathy, Alexander Shtov, Jenny Chen, Anke Stöltzel, Bennett J. Christensen, Shimon Kolkowitz   +8 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source