Results 81 to 90 of about 2,444,499 (343)

Roadmap of ultrafast x-ray atomic and molecular physics

, 2018
X-ray free-electron lasers (XFELs) and table-top sources of x-rays based upon high harmonic generation (HHG) have revolutionized the field of ultrafast x-ray atomic and molecular physics, largely due to an explosive growth in capabilities in the past ...
L. Young, K. Ueda, M. Gühr, P. Bucksbaum, M. Simon, S. Mukamel, N. Rohringer, K. Prince, C. Masciovecchio, M. Meyer, A. Rudenko, D. Rolles, C. Bostedt, M. Fuchs, D. Reis, R. Santra, H. Kapteyn, M. Murnane, H. Ibrahim, F. Légaré, M. Vrakking, M. Isinger, D. Kroon, M. Gisselbrecht, A. L’Huillier, H. Wörner, S. Leone   +26 more
semanticscholar   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Strongly Bound Frenkel Excitons on TiO2 Nanoparticles: An Evolutionary and DFT Approach

International Journal of Photoenergy
An evolutionary algorithm was employed to locate the global minimum of TiO2n nanoparticles with n=2–20. More than 61,000 structures were calculated with a semiempirical method and reoptimized using density functional theory. The exciton binding energy of
Oscar Olvera-Neria, Raúl García-Cruz, Julio Gonzalez-Torres, Luz María García-Cruz, Jean Luis Castillo-Sánchez, Enrique Poulain   +5 more
doaj   +1 more source

Search for transient ultralight dark matter signatures with networks of precision measurement devices using a Bayesian statistics method

, 2018
We analyze the prospects of employing a distributed global network of precision measurement devices as a dark matter and exotic physics observatory. In particular, we consider the atomic clocks of the Global Positioning System (GPS), consisting of a ...
Blewitt, G., Dailey, C., Derevianko, A., Roberts, B. M.   +3 more
core   +1 more source

Roadmap on photonic, electronic and atomic collision physics: I. Light–matter interaction

Journal of Physics B: Atomic, Molecular and Optical Physics, 2019
We publish three Roadmaps on photonic, electronic and atomic collision physics in order to celebrate the 60th anniversary of the ICPEAC conference. In Roadmap I, we focus on the light–matter interaction.
K. Ueda, E. Sokell, S. Schippers, F. Aumayr, H. Sadeghpour, J. Burgdörfer, C. Lemell, X. Tong, T. Pfeifer, F. Calegari, A. Palacios, Fernando Martín, P. Corkum, G. Sansone, E. Gryzlova, A. Grum-Grzhimailo, M. Piancastelli, P. Weber, T. Steinle, K. Amini, J. Biegert, N. Berrah, E. Kukk, R. Santra, A. Müller, D. Dowek, R. Lucchese, C. W. McCurdy, P. Bolognesi, L. Avaldi, T. Jahnke, M. S. Schöf, er, R. Dörner, Y. Mairesse, L. Nahon, O. Smirnova, T. Schlathölter, E. Campbell, J. Rost, M. Meyer, Kazuo A. Tanaka   +41 more
semanticscholar   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Penning-Trap Mass Measurements in Atomic and Nuclear Physics

Annual Review of Nuclear and Particle Science, 2018
Penning-trap mass spectrometry in atomic and nuclear physics has become a well-established and reliable tool for the determination of atomic masses. In combination with short-lived radioactive nuclides it was first introduced at ISOLTRAP at the Isotope ...
J. Dilling, K. Blaum, M. Brodeur, S. Eliseev   +3 more
semanticscholar   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source