Results 81 to 90 of about 26,804,949 (344)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Atomic Energy Commission Report AECD-3792
Report discussing the progress of various projects at the Knolls Atomic Power Laboratory during the period from March to May ...
Knolls Atomic Power Laboratory
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Atomic Energy Commission Reports [PDF]
From introduction: "this is the fifth of a series of quarterly reports which will cover the progress and results from the conceptual design, economic evaluations and research and development work performed by the General Electric Company as part of the ...
U.S. Atomic Energy Commission
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Atomic Energy Commission Report TID-7546 Book 1
Preface: The Fuel Elements Conference held in Paris, France, November 18 to 23, 1957, under the joint sponsorship of the U.S. Atomic Energy Commission and the French Commissarat à l'Energie Atomique (CEA), provided an intensive review of fuel-element ...
U.S. Atomic Energy Commission
core
Data on Stark Broadening of Sn II Spectral Lines
Data on spectral line widths and shifts broadened by interactions with charged particles, for 44 lines in the spectrum of ionized tin, for collisions with electrons and H II and HeII ions, are presented as online available tables.
Milan S. Dimitrijević +3 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
This paper reviews several basic emission properties of the UV emission lines observed in the spectra of quasars and type-1 active galactic nuclei, mainly as a function of the ionization parameter, metallicity, and density of the emitting gas.
Paola Marziani +4 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

