Results 81 to 90 of about 112,044 (333)

Analysis of the Possibility of Disinfecting Surfaces Using Portable Foggers in the Era of the SARS-CoV-2 Epidemic

open access: yesEnergies, 2021
The SARS-CoV-2 pandemic has resulted in the need for increased surface disinfection. For this purpose, biocides, UV-C radiation, or ozonation can be used.
Marek Ochowiak   +5 more
doaj   +1 more source

Comparison of fibre optical measurements and discrete element simulations for the study of granulation in a spout fluidized bed [PDF]

open access: yes, 2006
Spout fluidized beds are frequently used for the production of granules or particles through granulation. The products find application in a large variety of applications, for example detergents, fertilizers, pharmaceuticals and food.
Deen, N.G.   +9 more
core   +4 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

The limitations of Slater's element-dependent exchange functional from analytic density functional theory

open access: yes, 2005
Our recent formulation of the analytic and variational Slater-Roothaan (SR) method, which uses Gaussian basis sets to variationally express the molecular orbitals, electron density and the one body effective potential of density functional theory, is ...
Brett I. Dunlap   +4 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Secondary atomization behavior and size distribution of emulsified fuel in spray flow under N2

open access: yesNihon Kikai Gakkai ronbunshu, 2015
In this study, secondary atomization of emulsified fuel spray was visualized, and the effect of ambient temperature on secondary atomization in spray flow was investigated.
Yutaka SHOJI   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Machine Learning of Molecular Electronic Properties in Chemical Compound Space [PDF]

open access: yes, 2013
The combination of modern scientific computing with electronic structure theory can lead to an unprecedented amount of data amenable to intelligent data analysis for the identification of meaningful, novel, and predictive structure-property relationships.
Gobre, Vivekanand   +7 more
core   +5 more sources

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