Results 11 to 20 of about 321,909 (338)
Cutis, 2021 A) Pink scaling plaques and erythematous erosions in the antecubital fossae of a 6-year-old White boy. B) Violaceous, hyperpigmented, nummular plaques on the back and extensor surface of the right arm of a 16-month-old Black girl. C) Atopic dermatitis and follicular prominence/accentuation on the neck of a young Black girl.
S. Ständer
semanticscholar +7 more sources
Lancet, TheAbstract Atopic dermatitis (AD) is a common, chronic skin disorder that can significantly impact the quality of life (QoL) of affected individuals as well as their families. Although the pathogenesis of the disorder is not yet completely understood, it appears to result from the complex interplay between defects in skin barrier function ...
E Guttman-Yassky +2 more
exaly +7 more sources
Atopic dermatitis: an expanding therapeutic pipeline for a complex disease
Nature reviews. Drug discovery, 2021 Atopic dermatitis (AD) is a common chronic inflammatory skin disease with a complex pathophysiology that underlies a wide spectrum of clinical phenotypes. AD remains challenging to treat owing to the limited response to available therapies.
T. Bieber
semanticscholar +1 more source
Molecular Mechanisms of Atopic Dermatitis Pathogenesis
International Journal of Molecular Sciences, 2021 Atopic dermatitis is a chronic, non-infectious inflammatory dermatosis. Acharacteristic feature is persistent itching of the skin. The chronic, relapsing course of the disease, economic burden, and the whole family’s involvement in the treatment process ...
Jowita Sroka-Tomaszewska, M. Trzeciak
semanticscholar +1 more source
Comorbidities of atopic dermatitis-what does the evidence say?
Journal of Allergy and Clinical Immunology, 2023 Atopic dermatitis (AD) is a common disease that is associated with atopic and nonatopic comorbidities. There has been a growing interest in this area of AD, because presence or risk of comorbidities can in many ways impact the management of patients with
J. Thyssen +4 more
semanticscholar +1 more source
JAK Inhibitors in the Treatment of Atopic Dermatitis.
Journal of Allergy and Clinical Immunology, 2021 Atopic dermatitis is a chronic inflammatory skin disorder associated with heterogenous presentation and often immense patient burden. Safe, targeted treatment options are currently limited.
Luiza de Bortolli Nogueira +5 more
semanticscholar +1 more source
Atopic and non-atopic eczema [PDF]
BMJ, 2006 Atopic eczema is a chronic, relapsing, inflammatory skin condition associated with epidermal barrier dysfunction. This article provides a summary of current knowledge on eczema and its management. We used the following sources of information to write this review: Atopic eczema and atopic dermatitis are terms that have been used synonymously (for a ...
Brown, Sara, Reynolds, Nick J.
openaire +3 more sources
British Journal of Dermatology, 2020 Tralokinumab, a fully human monoclonal antibody, specifically neutralizes interleukin‐13, a key cytokine driving peripheral inflammation in atopic dermatitis (AD). In phase II studies, tralokinumab combined with topical corticosteroids provided early and
A. Wollenberg +21 more
semanticscholar +1 more source
Prevalence and Incidence of Atopic Dermatitis: A Systematic Review
Acta Dermato-Venereologica, 2020 The primary objective of this study was to systematically review and analyse epidemiological studies of the prevalence and incidence of atopic dermatitis (AD) during childhood and adulthood, focusing on data from the 21st century.
Simon B A Bylund +3 more
semanticscholar +1 more source
Novel insights into atopic dermatitis.
Journal of Allergy and Clinical Immunology, 2022 Recent research into the pathophysiology and treatment of atopic dermatitis (AD) has shown notable progress. An increasing number of aspects of the immune system are being implicated in AD, including the epithelial barrier, TH2 cytokines, and mast cells.
Charles F. Schuler +4 more
semanticscholar +1 more source