JAK3 as an emerging target for topical treatment of inflammatory skin diseases [PDF]
, 2016 The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Alves de Medeiros, Ana +5 more
core +2 more sources
Periostin deletion suppresses late-phase response in mouse experimental allergic conjunctivitis
Allergology International, 2019 Background: To investigate the potential roles of periostin (POSTN), an extracellular matrix preferentially expressed in Th2-skewed conditions in the pathophysiology of allergic conjunctivitis.
Yosuke Asada +10 more
doaj +1 more source
Inflammatory cytokines and biofilm production sustain Staphylococcus aureus outgrowth and persistence: A pivotal interplay in the pathogenesis of Atopic Dermatitis [PDF]
, 2018 Individuals with Atopic dermatitis (AD) are highly susceptible to Staphylococcus aureus colonization. However, the mechanisms driving this process as well as the impact of S. aureus in AD pathogenesis are still incompletely understood.
A Matlow +88 more
core +1 more source
Diagnostic Features of Atopic Dermatitis
Acta Dermato-Venereologica, 1980 is missing.
J. Hanifin, G. Rajka
semanticscholar +1 more source
Journal of the European Academy of Dermatology and Venereology, 2020 Atopic dermatitis (AD) is a highly pruritic, chronic inflammatory skin disease. The diagnosis is made using evaluated clinical criteria. Disease activity and burden are best measured with a composite score, assessing both objective and subjective ...
A. Wollenberg +27 more
semanticscholar +1 more source
The clinical meaning of histamine skin reactivity [PDF]
, 2015 The definition of the “atopic state”, i.e. subjects presenting at least one skin wheal with a minimum diameter of 3 mm induced by an allergen skin-prick test (ASPT), is based on the assumption that wheal size depends entirely on the amount of histamine
BARRETO, Mario, RONCHETTI, ROBERTO
core +1 more source
Role of serum melatonin and oxidative stress in childhood atopic dermatitis: A prospective study
Indian Dermatology Online Journal, 2020 Background: Many factors have been implicated in the pathogenesis of atopic dermatitis (AD) and recently the role of oxidative damage has been postulated.
Shanthy Devadasan +3 more
doaj +1 more source
Sex hormones in allergic conjunctivitis: altered levels of circulating androgens and estrogens in children and adolescents with vernal keratoconjunctivitis [PDF]
, 2015 PURPOSE: Vernal keratoconjunctivitis (VKC) is a chronic allergic disease mainly affecting boys in prepubertal age and usually recovering after puberty.
Bonini, S. +4 more
core +4 more sources
Skin Barrier Abnormalities and Immune Dysfunction in Atopic Dermatitis
International Journal of Molecular Sciences, 2020 Atopic dermatitis (AD) is a common and relapsing skin disease that is characterized by skin barrier dysfunction, inflammation, and chronic pruritus. While AD was previously thought to occur primarily in children, increasing evidence suggests that AD is ...
Gabsik Yang +5 more
semanticscholar +1 more source
Risk factors for atopic eczema in school children Fatores de risco para eczema atópico em escolares
Revista Brasileira de Saúde Materno Infantil, 2005 OBJECTIVES: to study risk factors related to atopic eczema (AE) in school children of São Paulo. METHODS: 1972 parents or guardians of 6-7 years old children in the Southern Central area of São Paulo answered to a written questionnaire (standardized ...
Gustavo F. Wandalsen +4 more
doaj +1 more source