The clinical meaning of histamine skin reactivity [PDF]
The definition of the “atopic state”, i.e. subjects presenting at least one skin wheal with a minimum diameter of 3 mm induced by an allergen skin-prick test (ASPT), is based on the assumption that wheal size depends entirely on the amount of histamine
BARRETO, Mario, RONCHETTI, ROBERTO
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Prenatal Vitamin D Supplementation and Child Respiratory Health: A Randomised Controlled Trial [PDF]
PMCID: PMC3691177This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Merewood +38 more
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Background: In studies on allergies in mouse models, IgE production is an essential parameter to be evaluated. Here, we examine the effect of commercially available immunoreaction enhancer solutions and different blocking reagents in enzyme-linked ...
Toshiro Takai +11 more
doaj +1 more source
In addition to its antimicrobial activity, the skin-derived antimicrobial peptide human β-defensin-3 (hBD-3) promotes keratinocyte proliferation and migration to initiate the wound healing process; however, its effects on fibroblasts, which are the major
Miho Takahashi +18 more
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Distinguishing Asthma Phenotypes Using Machine Learning Approaches. [PDF]
Asthma is not a single disease, but an umbrella term for a number of distinct diseases, each of which are caused by a distinct underlying pathophysiological mechanism. These discrete disease entities are often labelled as asthma endotypes.
A Custovic +97 more
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A systematic review of associations between environmental exposures and development of asthma in children aged up to 9 years [PDF]
Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.Peer reviewedPublisher ...
AlKandari, F +7 more
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Staphylococcal enterotoxin sensitization in a community-based population : a potential role in adult-onset asthma [PDF]
Background: Recent studies suggest that Staphylococcus aureus enterotoxin sensitization is a risk factor for asthma. However, there is a paucity of epidemiologic evidence on adult-onset asthma in community-based populations.
Bachert, Claus +11 more
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Pollen grains induce a rapid and biphasic eczematous immune response in atopic eczema patients [PDF]
Introduction: Eczematous reactions to type I allergy-inducing antigens are documented in a subgroup of patients with atopic eczema. Yet, the underlying immunological mechanisms are not well understood.
Behrendt, Heidrun +7 more
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Involvement of PU.1 in NFATc1 promoter function in osteoclast development
Background: The transcription factors NFATc1 and PU.1 play important roles in osteoclast development. NFATc1 and PU.1 transactivate osteoclast-specific gene expression and a deficiency in NFATc1 or PU.1 genes causes osteopetrosis due to an insufficient ...
Kentaro Ishiyama +12 more
doaj +1 more source
Insulin Resistance Increases Serum Immunoglobulin E Sensitization in Premenopausal Women [PDF]
Background Although studies have shown that obesity is associated with aeroallergen sensitization (atopy), controversy still exists. We aimed to investigate the association between metabolic status, obesity, and atopy stratified by sex and menopausal ...
Seung Eun Lee +3 more
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