Associations of wheezing phenotypes in the first 6 years of life with atopy, lung function and airway responsiveness in mid-childhood [PDF]
<p>Background: Patterns of wheezing during early childhood may indicate differences in aetiology and prognosis of respiratory illnesses. Improved characterisation of wheezing phenotypes could lead to the identification of environmental influences ...
Heron, J +24 more
core +1 more source
Involvement of PU.1 in Mast Cell/Basophil-Specific Function of the Human IL1RL1/ST2 Promoter
Background: The human IL1RL1/ST2 gene encodes IL33 receptor. Recently, IL33 has been recognized as a key molecule for the development of Th2 response. Although mast cells and basophils are major targets of IL33 and play important roles in IL33-mediated ...
Yosuke Baba +11 more
doaj +1 more source
Lower expression of TLR2 and SOCS-3 is associated with Schistosoma haematobium infection and with lower risk for allergic reactivity in children living in a rural area in Ghana. [PDF]
BACKGROUND: Helminth infections are prevalent in rural areas of developing countries and have in some studies been negatively associated with allergic disorders and atopy. In this context little is known of the molecular mechanisms of modulation involved.
Larbi, Irene A. +42 more
core +1 more source
Insulin Resistance Increases Serum Immunoglobulin E Sensitization in Premenopausal Women [PDF]
Background Although studies have shown that obesity is associated with aeroallergen sensitization (atopy), controversy still exists. We aimed to investigate the association between metabolic status, obesity, and atopy stratified by sex and menopausal ...
Seung Eun Lee +3 more
doaj +1 more source
Exercise-induced bronchospasm and atopy in Ghana: Two surveys ten years apart [PDF]
Background: Asthma and allergic diseases have increased in the developed countries. It is important to determine whether the same trends are occurring in the developing countries in Africa.
Baffoe-Bonnie, Benjamin +23 more
core +1 more source
A comprehensive analysis of interleukin-4 receptor polymorphisms and their association with atopy and IgE regulation in childhood [PDF]
Background: The interleukin (IL) 4/IL13 pathway is involved in the regulation of IgE production associated with atopic diseases. Numerous polymorphisms have been identified in the coding region of the IL4 receptor alpha chain (IL4Ra) and previous ...
Kabesch, Michael +7 more
core +1 more source
Risk factors for atopic and non-atopic asthma in a rural area of Ecuador [PDF]
Background: Asthma has emerged as an important public health problem of urban populations in Latin America. Epidemiological data suggest that a minority of asthma cases in Latin America may be associated with allergic sensitisation and that other ...
Oviedo, G +8 more
core +1 more source
Risk factors for asthma and allergy associated with urban migration: background and methodology of a cross-sectional study in Afro-Ecuadorian school children in Northeastern Ecuador (Esmeraldas-SCAALA Study). [PDF]
BACKGROUND: Asthma and allergic diseases are becoming increasingly frequent in children in urban centres of Latin America although the prevalence of allergic disease is still low in rural areas.
Cooper Philip J +51 more
core +2 more sources
Human Schistosome Infection and Allergic Sensitisation [PDF]
Several field studies have reported an inverse relationship between the prevalence of helminth infections and that of allergic sensitisation/atopy. Recent studies show that immune responses induced by helminth parasites are, to an extent, comparable to ...
Francisca Mutapi +5 more
core +1 more source
Anti-CD321 antibody immunotherapy protects liver against ischemia and reperfusion-induced injury
The prognosis of the liver transplant patients was frequently deteriorated by ischemia and reperfusion injury (IRI) in the liver. Infiltration of inflammatory cells is reported to play critical roles in the pathogenesis of hepatic IRI.
Enzhi Yin +10 more
doaj +1 more source

