Chronic virus infections supress atopy but not asthma in a set of children from a large Latin American city: a cross-section study. [PDF]
BACKGROUND: The prevalence of allergic diseases has increased over recent decades in affluent countries, but remains low in rural populations and some non-affluent countries.
Cruz Álvaro C +39 more
core +2 more sources
Associations of wheezing phenotypes in the first 6 years of life with atopy, lung function and airway responsiveness in mid-childhood [PDF]
<p>Background: Patterns of wheezing during early childhood may indicate differences in aetiology and prognosis of respiratory illnesses. Improved characterisation of wheezing phenotypes could lead to the identification of environmental influences ...
Heron, J +24 more
core +1 more source
Involvement of PU.1 in NFATc1 promoter function in osteoclast development
Background: The transcription factors NFATc1 and PU.1 play important roles in osteoclast development. NFATc1 and PU.1 transactivate osteoclast-specific gene expression and a deficiency in NFATc1 or PU.1 genes causes osteopetrosis due to an insufficient ...
Kentaro Ishiyama +12 more
doaj +1 more source
Toxocara seropositivity, atopy and wheezing in children living in poor neighbourhoods in urban Latin American. [PDF]
BACKGROUND: Toxocara canis and T. cati are parasites of dogs and cats, respectively, that infect humans and cause human toxocariasis. Infection may cause asthma-like symptoms but is often asymptomatic and is associated with a marked eosinophilia ...
Cruz, Álvaro Augusto +52 more
core +1 more source
Involvement of PU.1 in Mast Cell/Basophil-Specific Function of the Human IL1RL1/ST2 Promoter
Background: The human IL1RL1/ST2 gene encodes IL33 receptor. Recently, IL33 has been recognized as a key molecule for the development of Th2 response. Although mast cells and basophils are major targets of IL33 and play important roles in IL33-mediated ...
Yosuke Baba +11 more
doaj +1 more source
Lower expression of TLR2 and SOCS-3 is associated with Schistosoma haematobium infection and with lower risk for allergic reactivity in children living in a rural area in Ghana. [PDF]
BACKGROUND: Helminth infections are prevalent in rural areas of developing countries and have in some studies been negatively associated with allergic disorders and atopy. In this context little is known of the molecular mechanisms of modulation involved.
Larbi, Irene A +35 more
core +1 more source
Insulin Resistance Increases Serum Immunoglobulin E Sensitization in Premenopausal Women [PDF]
Background Although studies have shown that obesity is associated with aeroallergen sensitization (atopy), controversy still exists. We aimed to investigate the association between metabolic status, obesity, and atopy stratified by sex and menopausal ...
Seung Eun Lee +3 more
doaj +1 more source
Human Schistosome Infection and Allergic Sensitisation [PDF]
Several field studies have reported an inverse relationship between the prevalence of helminth infections and that of allergic sensitisation/atopy. Recent studies show that immune responses induced by helminth parasites are, to an extent, comparable to ...
Francisca Mutapi +5 more
core +1 more source
Anti-CD321 antibody immunotherapy protects liver against ischemia and reperfusion-induced injury
The prognosis of the liver transplant patients was frequently deteriorated by ischemia and reperfusion injury (IRI) in the liver. Infiltration of inflammatory cells is reported to play critical roles in the pathogenesis of hepatic IRI.
Enzhi Yin +10 more
doaj +1 more source
Wound healing is a complex, multiphase process crucial for restoring tissue integrity and functionality after injury. Among the emerging therapeutic approaches, antimicrobial peptides (AMPs) have shown substantial promise because of their dual role in ...
Alafate Abudouwanli +10 more
doaj +1 more source

