Estimation of Atopy and Allergies Among Sudanese Children with Asthma [PDF]
Background: Bronchial asthma is a chronic respiratory problem characterized by a reversible hyper-responsive airway obstruction that is provoked by allergens, infections, or nonspecific triggers.
Amani Elgadal, Omaima Nail
doaj +2 more sources
Effect of urban vs. rural residence on the association between atopy and wheeze in Latin America: findings from a case-control analysis. [PDF]
BACKGROUND: The association between atopy and asthma is attenuated in non-affluent populations, an effect that may be explained by childhood infections such as geohelminths.
Platts-Mills, TA +17 more
core +2 more sources
Background: In studies on allergies in mouse models, IgE production is an essential parameter to be evaluated. Here, we examine the effect of commercially available immunoreaction enhancer solutions and different blocking reagents in enzyme-linked ...
Toshiro Takai +11 more
doaj +1 more source
Mucosal Mast Cells as Key Effector Cells in Food Allergies
Mucosal mast cells (MMCs) localized in the intestinal mucosa play a key role in the development of IgE-mediated food allergies. Recent advances have revealed that MMCs are a distinctly different population from connective tissue mast cells localized in ...
Nobuhiro Nakano, Jiro Kitaura
doaj +1 more source
Ascaris lumbricoids Infection as a Risk Factor for Asthma and Atopy in Rural Bangladeshi Children. [PDF]
Controversy persists as to whether helminth infections cause or protect against asthma and atopy. The aim of this study was to investigate the effects of helminth infection on asthma and atopy among Bangladeshi children.
Persson, Lars Å +19 more
core +1 more source
In addition to its antimicrobial activity, the skin-derived antimicrobial peptide human β-defensin-3 (hBD-3) promotes keratinocyte proliferation and migration to initiate the wound healing process; however, its effects on fibroblasts, which are the major
Miho Takahashi +18 more
doaj +1 more source
Toxocara seropositivity, atopy and wheezing in children living in poor neighbourhoods in urban Latin American. [PDF]
BACKGROUND: Toxocara canis and T. cati are parasites of dogs and cats, respectively, that infect humans and cause human toxocariasis. Infection may cause asthma-like symptoms but is often asymptomatic and is associated with a marked eosinophilia ...
Cruz, Álvaro Augusto +52 more
core +1 more source
Effects of geohelminth infection and age on the associations between allergen-specific IgE, skin test reactivity and wheeze: a case-control study. [PDF]
BACKGROUND: Most childhood asthma in poor populations in Latin America is not associated with aeroallergen sensitization, an observation that could be explained by the attenuation of atopy by chronic helminth infections or effects of age.
Oviedo, G +19 more
core +1 more source
Chronic virus infections supress atopy but not asthma in a set of children from a large Latin American city: a cross-section study. [PDF]
BACKGROUND: The prevalence of allergic diseases has increased over recent decades in affluent countries, but remains low in rural populations and some non-affluent countries.
Cruz Álvaro C +39 more
core +2 more sources
Involvement of PU.1 in NFATc1 promoter function in osteoclast development
Background: The transcription factors NFATc1 and PU.1 play important roles in osteoclast development. NFATc1 and PU.1 transactivate osteoclast-specific gene expression and a deficiency in NFATc1 or PU.1 genes causes osteopetrosis due to an insufficient ...
Kentaro Ishiyama +12 more
doaj +1 more source

