Results 11 to 20 of about 42,966 (197)

Estimation of Atopy and Allergies Among Sudanese Children with Asthma [PDF]

Sudan Journal of Medical Sciences, 2023
Background: Bronchial asthma is a chronic respiratory problem characterized by a reversible hyper-responsive airway obstruction that is provoked by allergens, infections, or nonspecific triggers.
Amani Elgadal, Omaima Nail
doaj   +2 more sources

Environmental Exposure to Endotoxin and Decreased Risk of Childhood Atopy

Allergology International, 2005
The hygiene hypothesis implies, in immunological terms, that microbial stimulation in early life skews the immune system towards the development of a T helper type 1 (Th1)-type lymphocyte population, and away from a T helper type 2 (Th2)-type development
Tatsuo Sakamoto, Soichiro Yata, Izumi Hirose, Masaki Futamura, Masashi Morishita, Komei Ito   +5 more
doaj   +2 more sources

Effect of urban vs. rural residence on the association between atopy and wheeze in Latin America: findings from a case-control analysis. [PDF]

, 2014
BACKGROUND: The association between atopy and asthma is attenuated in non-affluent populations, an effect that may be explained by childhood infections such as geohelminths.
Vaca, M., Workman, L, Platts-Mills, T. A. E., Workman, L., Rodrigues, LC, Vaca, M, Chico, ME, Platts-Mills, TAE, Cooper, P. J., Barreto, ML, Barreto, Maurício Lima, Chico, M. E., Endara, P, Cooper, PJ, Endara, P., Rodrigues, Laura Cunha, Cooper, Philip John, Platts-Mills, TA   +17 more
core   +2 more sources

Topical Gynura procumbens as a Novel Therapeutic Improves Wound Healing in Diabetic Mice

Plants, 2021
Nonhealing wounds are major socioeconomic challenges to healthcare systems worldwide. Therefore, there is a substantially unmet need to develop new drugs for wound healing.
Nutda Sutthammikorn, Volaluck Supajatura, Hainan Yue, Miho Takahashi, Sunee Chansakaow, Nobuhiro Nakano, Pu Song, Takasuke Ogawa, Shigaku Ikeda, Ko Okumura, Hideoki Ogawa, François Niyonsaba   +11 more
doaj   +1 more source

Epicutaneous Administration of Papain Induces IgE and IgG Responses in a Cysteine Protease Activity-Dependent Manner

Allergology International, 2014
Background: Epicutaneous sensitization to allergens is important in the pathogenesis of not only skin inflammation such as atopic dermatitis but also "atopic march" in allergic diseases such as asthma and food allergies.
Hideo Iida, Toshiro Takai, Yusuke Hirasawa, Seiji Kamijo, Sakiko Shimura, Hirono Ochi, Izumi Nishioka, Natsuko Maruyama, Hideoki Ogawa, Ko Okumura, Shigaku Ikeda   +10 more
doaj   +1 more source

Ascaris lumbricoids Infection as a Risk Factor for Asthma and Atopy in Rural Bangladeshi Children. [PDF]

, 2014
Controversy persists as to whether helminth infections cause or protect against asthma and atopy. The aim of this study was to investigate the effects of helminth infection on asthma and atopy among Bangladeshi children.
Persson, Lars Å, Noguchi, Emiko,, Itoh, Makoto,, Noguchi, Emiko, Wagatsuma, Yukiko,, Raqib, Rubhana,, Wagatsuma, Yukiko, Ma, Enbo, Moore, Sophie E; id_orcid, Moore, Sophie E,, Moore, Sophie E, Persson, Lars-Åke,, Raqib, Rubhana, Hawlader, Mohammad D H, Hawlader, Mohammad D H,, Arifeen, Shams E,, Arifeen, Shams E, Ma, Enbo,, Itoh, Makoto, Hawlader, Mohammad DH   +19 more
core   +1 more source

Enzyme-Linked Immunosorbent Assays with High Sensitivity for Antigen-Specific and Total Murine IgE: A Useful Tool for the Study of Allergies in Mouse Models

Allergology International, 2009
Background: In studies on allergies in mouse models, IgE production is an essential parameter to be evaluated. Here, we examine the effect of commercially available immunoreaction enhancer solutions and different blocking reagents in enzyme-linked ...
Toshiro Takai, Yuri Ochiai, Saori Ichikawa, Emi Sato, Takasuke Ogawa, Tomoko Tokura, Takatoshi Kuhara, Hiroshi Kawai, Hideki Hatanaka, Seizo Takahashi, Hideoki Ogawa, Ko Okumura   +11 more
doaj   +1 more source

Mucosal Mast Cells as Key Effector Cells in Food Allergies

Cells, 2022
Mucosal mast cells (MMCs) localized in the intestinal mucosa play a key role in the development of IgE-mediated food allergies. Recent advances have revealed that MMCs are a distinctly different population from connective tissue mast cells localized in ...
Nobuhiro Nakano, Jiro Kitaura
doaj   +1 more source

The Antimicrobial Peptide Human β-Defensin-3 Accelerates Wound Healing by Promoting Angiogenesis, Cell Migration, and Proliferation Through the FGFR/JAK2/STAT3 Signaling Pathway

Frontiers in Immunology, 2021
In addition to its antimicrobial activity, the skin-derived antimicrobial peptide human β-defensin-3 (hBD-3) promotes keratinocyte proliferation and migration to initiate the wound healing process; however, its effects on fibroblasts, which are the major
Miho Takahashi, Miho Takahashi, Yoshie Umehara, Hainan Yue, Hainan Yue, Juan Valentin Trujillo-Paez, Ge Peng, Ge Peng, Hai Le Thanh Nguyen, Hai Le Thanh Nguyen, Risa Ikutama, Risa Ikutama, Ko Okumura, Hideoki Ogawa, Hideoki Ogawa, Shigaku Ikeda, Shigaku Ikeda, François Niyonsaba, François Niyonsaba   +18 more
doaj   +1 more source

Effects of geohelminth infection and age on the associations between allergen-specific IgE, skin test reactivity and wheeze: a case-control study. [PDF]

, 2013
BACKGROUND: Most childhood asthma in poor populations in Latin America is not associated with aeroallergen sensitization, an observation that could be explained by the attenuation of atopy by chronic helminth infections or effects of age.
Oviedo, G, Platts-Mills, TA, Vaca, M., Workman, L. J., Platts-Mills, T. A. E., Barreto, M. L., Rodrigues, LC, Moncayo, A-L, Workman, LJ, Vaca, M, Chico, ME, Platts-Mills, TAE, Oviedo, G., Barreto, ML, Moncayo, AL, Rodrigues, L. C., Chico, M. E., Cooper, PJ, Cooper, Philip, Moncayo, A.-L.   +19 more
core   +1 more source