Results 21 to 30 of about 79,824 (366)

CX3CR1 Polymorphisms are associated with atopy but not asthma in German children [PDF]

, 2007
Chemokines and their receptors are involved in many aspects of immunity. Chemokine CX3CL1, acting via its receptor CX3CR1, regulates monocyte migration and macrophage differentiation as well as T cell-dependent inflammation.
Christian Vogelberg, Christophe Combadière, Combadiere C, Daoudi M, Davis CN, Erika von Mutius, Fraticelli P, Fujimoto K, Kormann MS, Laprise C, Martin Depner, Michael Kabesch, Michael S.D. Kormann, Moatti D, Niess JH, Norman Klopp, Rimaniol AC, Simpson A, Stephan K. Weiland, Thomas Illig, Tremblay K   +20 more
core   +2 more sources

Staphylococcal enterotoxin sensitization in a community-based population : a potential role in adult-onset asthma [PDF]

, 2014
Background: Recent studies suggest that Staphylococcus aureus enterotoxin sensitization is a risk factor for asthma. However, there is a paucity of epidemiologic evidence on adult-onset asthma in community-based populations.
Bachert, Claus, Chang, Yoon-Seok, Cho, Sang-Heon, Choi, Min-Ho, Kang, Hye-Ryun, Kim, Sae-Hoon, Lim, Min Kyung, Min, Kyung-Up, Park, Heung-Woo, Song, Woo-Jung, Tomassen, Peter, Yun, E Hwa   +11 more
core   +2 more sources

Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses

Journal of Experimental Medicine, 2019
Spencer et al. report the first description of human IL-6R deficiency in two patients presenting with recurrent infections, atopy, elevated IgE, and abnormal acute-phase responses.
Sarah Spencer, S. Köstel Bal, W. Egner, Hana Lango Allen, S. I. Raza, Chi A. Ma, Meltem Gürel, Y. Zhang, Guangping Sun, R. Sabroe, D. Greene, W. Rae, T. Shahin, Katarzyna Kania, R. Ardy, M. Thian, E. Staples, A. Pecchia-Bekkum, William P M Worrall, J. Stephens, M. Brown, Salih Tuna, M. York, F. Shackley, D. Kerrin, R. Sargur, Alison M Condliffe, H. N. Tipu, H. Kuehn, S. Rosenzweig, E. Turro, S. Tavaré, A. Thrasher, D. Jodrell, Kenneth G. C. Smith, K. Boztug, J. Milner, James E. D. Thaventhiran   +37 more
semanticscholar   +1 more source

The clinical meaning of histamine skin reactivity [PDF]

, 2015
The definition of the “atopic state”, i.e. subjects presenting at least one skin wheal with a minimum diameter of 3 mm induced by an allergen skin-prick test (ASPT), is based on the assumption that wheal size depends entirely on the amount of histamine
BARRETO, Mario, RONCHETTI, ROBERTO
core   +1 more source

Involvement of PU.1 in NFATc1 promoter function in osteoclast development

Allergology International, 2015
Background: The transcription factors NFATc1 and PU.1 play important roles in osteoclast development. NFATc1 and PU.1 transactivate osteoclast-specific gene expression and a deficiency in NFATc1 or PU.1 genes causes osteopetrosis due to an insufficient ...
Kentaro Ishiyama, Takuya Yashiro, Nobuhiro Nakano, Kazumi Kasakura, Ryosuke Miura, Mutsuko Hara, Fumitaka Kawai, Keiko Maeda, Naoto Tamura, Ko Okumura, Hideoki Ogawa, Yoshinari Takasaki, Chiharu Nishiyama   +12 more
doaj   +1 more source

Involvement of PU.1 in Mast Cell/Basophil-Specific Function of the Human IL1RL1/ST2 Promoter

Allergology International, 2012
Background: The human IL1RL1/ST2 gene encodes IL33 receptor. Recently, IL33 has been recognized as a key molecule for the development of Th2 response. Although mast cells and basophils are major targets of IL33 and play important roles in IL33-mediated ...
Yosuke Baba, Keiko Maeda, Takuya Yashiro, Eisuke Inage, Frangois Niyonsaba, Mutsuko Hara, Ryuyo Suzuki, Yoshikazu Ohtsuka, Toshiaki Shimizu, Hideoki Ogawa, Ko Okumura, Chiharu Nishiyama   +11 more
doaj   +1 more source

Distinguishing Asthma Phenotypes Using Machine Learning Approaches. [PDF]

, 2015
Asthma is not a single disease, but an umbrella term for a number of distinct diseases, each of which are caused by a distinct underlying pathophysiological mechanism. These discrete disease entities are often labelled as asthma endotypes.
A Custovic, A Custovic, A Fraser, A Høst, A Pickles, A Simpson, A Wijga, Adnan Custovic, AJ Lowe, AV Berg, B Clarisse, BD Spycher, BD Spycher, BD Spycher, BG Toelle, BL Jones, BL Jones, C-M Chen, CA Figueiredo, CE Kuehni, CJ Lodge, CL Storr, D Barber, D Belgrave, D Caudri, D Nagin, DA Linzer, DC Belgrave, DC Belgrave, DCM Belgrave, DCM Belgrave, F Kauffmann, F Kauffmann, FD Martinez, FL Garden, FP Perera, G Bochenek, G Weinmayr, GB Marks, GP Anderson, J Hagenaars, J Henderson, J Lotvall, J Magidson, J Sunyer, J Winn, JA Smith, JK Vermunt, K Burnham, KE Wonderen Van, KL Nylund, L García-Marcos Álvarez, L Hunt, L Lowe, L Panico, LA Lowe, M Depner, M Herr, M Scott, Magnus Rattray, Mattia Prosperi, MJ Ege, ML Barreto, MM Hagendorens, MW Pijnenburg, N Lazic, NC Nicolaou, NG Papadopoulos, OE Savenije, P Burney, P Haldar, P Rzehak, P Rzehak, PD Sly, Q Chen, Q Vuong, Rebecca Howard, RJP Valk van der, RL Bergmann, RL Miller, RO Crapo, RT Stein, S American Thoracic, S Havstad, S Mihrshahi, S Rabe-Hesketh, S Stanojevic, SE Wenzel, SK Weiland, ST Lanza, ST Lanza, T Jung, T Minka, The European Community Respiratory Health Survey, V Siroux, WC Moore, X Robin, Y Lo   +97 more
core   +1 more source

Anti-CD321 antibody immunotherapy protects liver against ischemia and reperfusion-induced injury

Scientific Reports, 2021
The prognosis of the liver transplant patients was frequently deteriorated by ischemia and reperfusion injury (IRI) in the liver. Infiltration of inflammatory cells is reported to play critical roles in the pathogenesis of hepatic IRI.
Enzhi Yin, Takeshi Fukuhara, Kazuyoshi Takeda, Yuko Kojima, Kyoko Fukuhara, Kenichi Ikejima, Hisashi Bashuda, Jiro Kitaura, Hideo Yagita, Ko Okumura, Koichiro Uchida   +10 more
doaj   +1 more source

A systematic review of associations between environmental exposures and development of asthma in children aged up to 9 years [PDF]

, 2014
Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.Peer reviewedPublisher ...
AlKandari, F, Ayres, J G, Cowie, H, Dick, S, Doust, E, Dynes, K, Friend, A, Turner, S W   +7 more
core   +1 more source

Histone modifications and their role in epigenetics of atopy and allergic diseases

Allergy, Asthma & Clinical Immunology, 2018
This review covers basic aspects of histone modification and the role of posttranslational histone modifications in the development of allergic diseases, including the immune mechanisms underlying this development.
Bilal Alaskhar Alhamwe, Razi Khalaila, Johanna Wolf, V. von Bülow, Hani Harb, Fahd Alhamdan, C. Hii, S. Prescott, A. Ferrante, H. Renz, H. Garn, D. P. Potaczek   +11 more
semanticscholar   +1 more source