Results 31 to 40 of about 59,745 (273)

Temporal Changes in Total Serum Immunoglobulin E Levels in East German Children and the Effect of Potential Predictors [PDF]

, 2011
Background: Elevated total serum immunoglobulin E (IgE) levels are a prominent feature of allergic and parasitic diseases. An epidemiologic study was conducted in East German children to describe trends in the development of total serum IgE levels and ...
Brüske, Irene, Flohrs, Katrin, Heinrich, Joachim, Rzehak, Peter, Thiering, Elisabeth, Wichmann, Heinz-Erich   +5 more
core   +1 more source

Long-term effects of allergen sensitization and exposure in adult asthma: a prospective study. [PDF]

, 2009
BACKGROUND: : We investigated the effects of sensitization and exposure to common domestic allergens on longitudinal changes in lung function and bronchial hyperresponsiveness. METHODS: : Subjects attended 2 visits that were 4 years apart.
Adnan Custovic, Angela Simpson, Antens, Ashley Woodcock, Asokananthan, Barter, Braun-Fahrlander, Chapman, Dijkstra, Fowler, Gehring, Gore, Grol, Juniper, Kharitonov, Lange, Langley, Langley, Luczynska, Masoli, Nicholas J. Truman, Salome, Schou, Simpson, Stephen J. Fowler, Stephen J. Langley, Taylor, Thorne, Vonk, Waser, Yan   +30 more
core   +1 more source

AMP-IBP5: A Multifunctional Antimicrobial Peptide for Advanced Wound Healing and Inflammatory Skin Disorders

Journal of Functional Biomaterials
Wound healing is a complex, multiphase process crucial for restoring tissue integrity and functionality after injury. Among the emerging therapeutic approaches, antimicrobial peptides (AMPs) have shown substantial promise because of their dual role in ...
Alafate Abudouwanli, Ge Peng, Mengyao Yang, Wanchen Zhao, Quan Sun, Shan Wang, Yi Tan, Arisa Ikeda, Hideoki Ogawa, Ko Okumura, François Niyonsaba   +10 more
doaj   +1 more source

Respiratory syncytial virus infection and bronchial hyperreactivity in children up to two years of age in correlation with atopy [PDF]

Vojnosanitetski Pregled, 2016
Background/Aim. Bronchiolitis in early childhood caused by respiratory syncytial virus (RSV) is considered to be important risk factor of the recurrent wheezing and asthma development.
Relić Tijana, Ilić Nevenka, Kostić Gordana, Jovanović Dara, Tambur Zoran, Lazarević Ivana   +5 more
doaj   +1 more source

CX3CR1 Polymorphisms are associated with atopy but not asthma in German children [PDF]

, 2007
Chemokines and their receptors are involved in many aspects of immunity. Chemokine CX3CL1, acting via its receptor CX3CR1, regulates monocyte migration and macrophage differentiation as well as T cell-dependent inflammation.
Christian Vogelberg, Christophe Combadière, Combadiere C, Daoudi M, Davis CN, Erika von Mutius, Fraticelli P, Fujimoto K, Kormann MS, Laprise C, Martin Depner, Michael Kabesch, Michael S.D. Kormann, Moatti D, Niess JH, Norman Klopp, Rimaniol AC, Simpson A, Stephan K. Weiland, Thomas Illig, Tremblay K   +20 more
core   +2 more sources

Prevalence and risk factors for atopic disease in a population of preschool children in Rome: Challenges to early intervention [PDF]

, 2016
Background: Allergic diseases are complex identities determined by an interplay of genetic and environmental factors, resulting in the clinical manifestation of the disease.
DE CASTRO, Giovanna, DE VITTORI, Valentina, Duse, Marzia, Forastiere, F, Indinnimeo, Luciana, Melengu, T, Porta, D, Tancredi, Giancarlo, Zicari, Anna Maria   +8 more
core   +1 more source

Gastrointestinal Manifestations in Rubinstein‐Taybi Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Rubinstein–Taybi syndrome is a rare genetic condition associated with a wide range of physical, cognitive, and developmental impairments, yet its gastrointestinal manifestations remain poorly characterized. Case reports and small series suggest a high prevalence of gastroesophageal reflux, constipation, dysphagia, and nutritional compromise ...
Mohamad Abi Nassif, Ajay Kaul, Lev Dorfman, Khalil El‐Chammas   +3 more
wiley   +1 more source

Rationale of New Grading System: Central Compartment Atopic Disease

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Central compartment atopic disease (CCAD) has recently been recognized as a distinct phenotype within the spectrum of type 2–dominant chronic rhinosinusitis (CRS). Although international guidelines highlight polypoid changes in the central nasal cavity, standardized diagnostic and classification criteria are still lacking.
Ramón Moreno‐Luna, Carmen Palma‐Martínez, Serafin Sánchez‐Gómez, Isam Alobid, Daniel Martin‐Jimenez, José Miguel Villacampa‐Aubá, Christian Calvo‐Henríquez, Alfonso Del Cuvillo, Alfonso Santamaría‐Gadea, Jaime González‐García, Richard J. Harvey, John M. DelGaudio   +11 more
wiley   +1 more source

Intranasal administration of ceramide liposome suppresses allergic rhinitis by targeting CD300f in murine models

Scientific Reports
Allergic rhinitis (AR) is caused by type I hypersensitivity reaction in the nasal tissues. The interaction between CD300f and its ligand ceramide suppresses immunoglobulin E (IgE)-mediated mast cell activation.
Takuma Ide, Kumi Izawa, Wahyu Diono, Anna Kamei, Tomoaki Ando, Ayako Kaitani, Akie Maehara, Akihisa Yoshikawa, Risa Yamamoto, Shino Uchida, Hexing Wang, Mayuki Kojima, Keiko Maeda, Nobuhiro Nakano, Masahiro Nakamura, Toshiaki Shimizu, Hideoki Ogawa, Ko Okumura, Fumihiko Matsumoto, Katsuhisa Ikeda, Motonobu Goto, Jiro Kitaura   +21 more
doaj   +1 more source

Neuronal substance P-driven MRGPRX2-dependent mast cell degranulation products differentially promote vascular permeability

Frontiers in Immunology
Mas-related G protein-coupled receptor b2 (Mrgprb2) binding to its cationic endogenous and exogenous ligands induces mast cell degranulation and promotes inflammation in mice. However, the physiological roles of its human homologue MRGPRX2 remain unclear.
Masakazu Nagamine, Masakazu Nagamine, Ayako Kaitani, Kumi Izawa, Tomoaki Ando, Akihisa Yoshikawa, Akihisa Yoshikawa, Masahiro Nakamura, Akie Maehara, Risa Yamamoto, Yoko Okamoto, Hexing Wang, Hexing Wang, Hiromichi Yamada, Hiromichi Yamada, Keiko Maeda, Keiko Maeda, Nobuhiro Nakano, Toshiaki Shimizu, Toshiaki Shimizu, Hideoki Ogawa, Ko Okumura, Jiro Kitaura, Jiro Kitaura   +23 more
doaj   +1 more source