Results 31 to 40 of about 56,049 (248)

Assessment of Response of Kidney Tumors to Rapamycin and Atorvastatin in Tsc1+/− Mice

open access: yesTranslational Oncology, 2017
Atorvastatin is widely used to lower blood cholesterol and to reduce risk of cardiovascular disease–associated complications. Epidemiological investigations and preclinical studies suggest that statins such as atorvastatin have antitumor activity for ...
Ming Hong Shen   +5 more
doaj   +1 more source

Add-on effect of probucol in atherosclerotic, cholesterol-fed rabbits treated with atorvastatin. [PDF]

open access: yesPLoS ONE, 2014
OBJECTIVE: Lowering the blood concentration of low-density lipoprotein (LDL) cholesterol is the primary strategy employed in treating atherosclerotic disorders; however, most commonly prescribed statins prevent cardiovascular events in just 30% to 40% of
Yuka Keyamura   +9 more
doaj   +1 more source

Pharmacokinetics and Genetic Factors of Atorvastatin in Healthy Korean Subjects

open access: yesFrontiers in Genetics, 2022
Background: Statins are the most popular agents for the primary and secondary prevention of cardiovascular disease; however, the pharmacokinetic parameters and associated genetic factors in the Korean population have not been fully elucidated. This study
Serim Kim   +11 more
doaj   +1 more source

Atorvastatin

open access: yesReactions Weekly, 2006
openaire   +2 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Combined Beneficial Effect of Genistein and Atorvastatin on Adipogenesis in 3T3-L1 Adipocytes

open access: yesBiomolecules, 2021
Genistein (4,5,7-trihydroxyisoflavone) is abundant in various dietary vegetables, especially soybeans, and is known to have not only an estrogenic effect but also an antiadipogenic effect.
Dahae Lee   +4 more
doaj   +1 more source

A placebo-controlled trial examining atorvastatin in dyslipidemic patients undergoing CAPD [PDF]

open access: yes, 2002
A placebo-controlled trial examining atorvastatin in dyslipidemic patients undergoing CAPD.BackgroundIndividuals with chronic renal disease are at high risk of cardiovascular morbidity and mortality, and therefore the management of dyslipidemia is ...
Harris, Kevin P.G.   +3 more
core   +1 more source

Sphingosine Kinase 1 Plays an Important Role in Atorvastatin-Mediated Anti-Inflammatory Effect against Acute Lung Injury

open access: yesMediators of Inflammation, 2021
Atorvastatin is a 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) inhibitor and inhibits cholesterol synthesis. Recently, atorvastatin also showed anti-inflammatory effect in acute lung injury, ameliorating pulmonary gas-blood ...
Lan Wu   +4 more
doaj   +1 more source

Thermodynamic and Thermomicroscopy Study of Atorvastatin Calcium-Succinic Acid Binary Mixtures

open access: yesIndonesian Journal of Chemistry, 2017
Binary mixtures of pharmaceuticals significantly affect the physical and chemical properties of each component. The aim of this work was to explore the thermal behavior and solid state transformation of binary mixture of atorvastatin calcium and succinic
Yudi Wicaksono   +3 more
doaj   +1 more source

Pharmacokinetic Interaction between Atorvastatin and Omega-3 Fatty Acid in Healthy Volunteers

open access: yesPharmaceuticals, 2022
The interaction between statins and omega-3 fatty acids remains controversial. The aim of this phase 1 trial was to evaluate the pharmacokinetics of drug-drug interaction between atorvastatin and omega-3 fatty acids.
Jae Hoon Kim   +10 more
doaj   +1 more source

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