Effect of atorvastatin on byssus production of the blue mussels, Mytilus edulis
, 2019 Increasing concentration of biologically active pharmaceutical compounds can affect marine organisms. The bioavailability and environmental stability of these compounds make them potential threat to these organisms, specially the sessile organisms.
Sabrina Glufke (7884569) +19 more
core +1 more source
In Vitro Blood-Brain-Barrier Permeability and Cytotoxicity of Atorvastatin-Loaded Nanoformulation Against Glioblastoma in 2D and 3D Models [PDF]
, 2019 Inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase of the family of statins have been suggested as therapeutic options in various tumors.
Michael M, Lübtow +14 more
core +2 more sources
Betulinic Acid Counteracts Statin‐Induced PCSK9 Upregulation Through FXR/SHP‐Associated Signaling
Phytotherapy Research, EarlyView.Betulinic acid attenuates atorvastatin‐induced increases in PCSK9 expression and secretion while maintaining or increasing LDLR expression in hepatocyte‐derived cells. Mechanistic studies support the involvement of FXR/SHP signaling and show increased SHP–SREBP2 association.
Chan‐Woong Park +6 more
wiley +1 more source
Atorvastatin and cardiovascular risk in the elderly – patient considerations
, 2008 Subroto Acharjee, Francine K WeltyDivision of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, USAAbstract: Elderly individuals are at increased risk of coronary heart disease (CHD) and account for a majority of CHD deaths.
Subroto Acharjee, Francine K Welty
core
Microfluidics Lab‐on‐a‐Chip Approaches to Decipher Atherosclerosis Pathogenesis
Small, EarlyView.Figure created with BioRender.com. This review highlights how microfluidic lab‐on‐a‐chip models recreate key features of atherosclerosis in controlled, human‐relevant environments. It summarizes advances in modeling endothelial dysfunction, immune cell recruitment, foam cell formation, vascular remodeling, stenosis, and plaque rupture.
Fahima Akther, Hang Thu Ta
wiley +1 more source
Effects of Catha edulis Extract on Atorvastatin-Induced Myotoxicity in Rats: Biochemical and Histopathological Evidence [PDF]
Abdulatef Mohammed Mohammed Abbas,1 Safia Abdulatef Abdulruhman Alrezami,1,2 Butheina Abdulwalli Al- Amrani3 1Department of Pharmacy, Faculty of Medicine and Health Science, University of AlMahweet, AlMahweet, Yemen; 2Department of Pharmacology and ...
Abbas AMM, Al- Amrani BA, Alrezami SAA
core
Atorvastatin attenuates ENA-78 production over time.
, 2013 Levels are relative to baseline (0 hour) for each condition. Data are presented as mean±SEM of 4 experiments. *p≤0.01. —○—, IL-1β stimulation+atorvastatin 10 µM; —•—, IL-1β stimulation alone; AT, atorvastatin.
Issam Zineh (53595) +8 more
core +1 more source
Sympathoinhibition by atorvastatin in hypertensive patients. [PDF]
, 2010 Contains fulltext : 89086.pdf (Publisher’s version ) (Open Access)BACKGROUND: Experimental animal data suggest that 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) might reduce enhanced sympathetic ...
Gomes, M.E.R. +9 more
core +1 more source
Advances in research on layered double hydroxides for biomedical applications
Smart Molecules, EarlyView.Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang +13 more
wiley +1 more source
Journal of Biomedical Science, 2009 Atorvastatin has been shown to reduce resistin expression in macrophages after pro-inflammatory stimulation. However, the mechanism of reducing resistin expression by atorvastatin is not known. Therefore, we sought to investigate the molecular mechanisms
Chua Su-Kiat +3 more
doaj +1 more source