Results 131 to 140 of about 57,678 (240)

Dose-dependent effects of atorvastatin on myocardial infarction

, 2015
Olga Barbarash, Olga Gruzdeva, Evgenya Uchasova, Ekaterina Belik, Yulia Dyleva, Victoria KaretnikovaFederal State Budgetary Institution, Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, the Russian Federation Background ...
Dyleva Y, Uchasova E, Karetnikova V, Belik E, Barbarash O, Gruzdeva O   +5 more
core  

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

Effects of non‐surgical periodontal therapy on intrabony periodontal defects at different re‐evaluation time points: A systematic review of randomized controlled trials and clinical recommendations

Periodontology 2000, EarlyView.
Abstract Objective The aim of this systematic review and meta‐analysis was to evaluate the longitudinal temporal pattern of periodontal probing depth (PPD) reduction in intrabony periodontal defects following non‐surgical periodontal therapy (NSPT), both as a monotherapy and with adjunctive locally delivered pharmacological agents.
Luca Ramaglia, Vincenzo Iorio‐Siciliano, Leopoldo Mauriello, Andrea Blasi, Anton Sculean   +4 more
wiley   +1 more source

Simultaneous administration of high-dose atorvastatin and clopidogrel does not interfere with platelet inhibition during percutaneous coronary intervention

, 2016
Rolf P Kreutz,1,2 Jeffrey A Breall,1 Anjan Sinha,1 Elisabeth von der Lohe,1 Richard J Kovacs,1 David A Flockhart,2,† 1Krannert Institute of Cardiology, 2Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, IN ...
Breall JA, Sinha A, Flockhart DA, Kovacs RJ, Kreutz RP, von der Lohe E   +5 more
core  

The effects of uninterrupted and interrupted sitting on blood pressure and arterial stiffness in patients with established coronary heart disease

Experimental Physiology, EarlyView.
Abstract Sedentary behaviour is an independent risk factor for cardiovascular disease. In healthy adults, prolonged uninterrupted sitting acutely increases blood pressure (BP) and aortic stiffness; however, these effects can be mitigated with light physical activity interruptions.
Simon Fryer, Eve Scarle, Louise Turner, Arsalan Moinuddin, James Faulkner, Hayley Legg, Craig Paterson, Keeron Stone   +7 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

The safety and tolerability of atorvastatin 10 mg in the Collaborative Atorvastatin Diabetes Study (CARDS)

, 2008
The objective of this study was to evaluate the safety and tolerability of atorvastatin 10 mg compared with placebo in 2,838 Patients with type 2 diabetes and no history of coronary heart disease who were enrolled in the Collaborative Atorvastatin ...
Newman, Connie B., Fuller, John H., Durrington, Paul N., Szarek, Michael, Neil, H. Andrew W., Neil, H. Andrew W, Betteridge, D. John, Colhoun, Helen M., Demicco, David A., Auster, Sheila, Hitman, Graham A.   +10 more
core   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, Volume 200, Issue 12, Page 2719-2737, December 2026.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

Toxicity of Atorvastatin on Isolated Brain Mitochondria: Neurotoxicity of Atorvastatin

, 2017
Background: Although the bio kinetics, metabolism and chemical toxicity of Atorvastatin are well known, until recently little attention was paid to the potential neurotoxic effect of Atorvastatin (Atv). Regarding the concrete evidences indicating Atv may
Sanaze Nasohi, Nafiseh Rahmanabadi, Banafsheh Saiid, Jalal Pourahmad, Parvaneh Naserzadeh   +4 more
core   +1 more source

Dyslipidaemia, Chronic Kidney Disease and Diabetes Mellitus: A Triple Threat to Cardiovascular Health

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 10961-10976, December 2026.
ABSTRACT Diabetes mellitus (DM) and chronic kidney disease (CKD) frequently coexist and together create a ‘triple threat’ with dyslipidaemia, enhancing the risk for cardiovascular morbidity and mortality. Diabetic kidney disease (DKD) leads to altered lipid metabolism through insulin resistance, inflammation and oxidative stress resulting in an ...
Ann S. Forrest, Priyanka Majety, Stéphanie B. Mayer, Om P. Ganda   +3 more
wiley   +1 more source