Results 131 to 140 of about 51,731 (234)

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods

Chirality, Volume 38, Issue 7, July 2026.
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz, Cigdem Karaaslan Kirmizioglu   +1 more
wiley   +1 more source

Atorvastatin in stroke: a review of SPARCL and subgroup analysis

, 2010
Branko N Huisa, Andrew B Stemer, Justin A ZivinDepartment of Neuroscience University of California, San Diego, CA, USAAbstract: Statin therapy in patients with cardiovascular disease is associated with reduced incidence of stroke.
Justin A Zivin, Branko N Huisa, Andrew B Stemer   +2 more
core  

Effect of interferon-beta and atorvastatin on Th1/Th2 cytokines in multiple sclerosis

, 2008
Beneficial effects by both interferon-beta and statin treatment in patients with multiple sclerosis (MS) may be linked to interference with the Th1/Th2 cytokine balance.
Grandgirard, Denis, Kamm, Christian P., Greeve, Isabell, Minten, Carsten, Sellner, Johann, Engelhardt, Britta, Leib, Stephen L., Findling, Oliver, Mattle, Heinrich P   +8 more
core   +1 more source

Can a Lifestyle‐Centred, Low‐Dose Model Improve Hypertension and Diabetes Care in Low‐ and Middle‐Income Countries? Real‐World Implementation Data From Zambia

Lifestyle Medicine, Volume 7, Issue 3, July 2026.
ABSTRACT Introduction Hypertension and Type 2 diabetes are major contributors to the growing burden of non‐communicable diseases in rural Zambia. Lifestyle interventions are central to prevention and management, yet implementation remains limited in resource‐constrained settings.
Keith Birrell, Ginny Birrell, Fastone Goma   +2 more
wiley   +1 more source

Correlation of atorvastatin with subjective memory deficits: a study from the NHANES and FAERS databases

Frontiers in Neurology
BackgroundPost-marketing regulatory data suggest a potential association between atorvastatin use and memory protection; however, findings from observational studies have been inconsistent and remain a subject of controversy.ObjectiveThis study aims to ...
Hao Zhang, Hua Huang, Panli Zhao
doaj   +1 more source

Limitations of real-world treatment with atorvastatin monotherapy for lowering LDL-C in high-risk cardiovascular patients in the US

, 2014
Elizabeth Marrett,1 Changgeng Zhao,1 Ning Jackie Zhang,2 Qiaoyi Zhang,1 Dena R Ramey,1 Joanne E Tomassini,1 Andrew M Tershakovec,1 David R Neff11Merck & Co, Inc., Whitehouse Station, NJ, USA; 2College of Health and Public Affairs, University of ...
Tomassini JE, Zhao C, Zhang NJ, Tershakovec AM, Neff DR, Marrett E, Zhang Q, Ramey DR   +7 more
core  

Direct adipotropic actions of atorvastatin: differentiation state-dependent induction of apoptosis, modulation of endocrine function, and inhibition of glucose uptake

, 2007
Statins exert anti-inflammatory, anti-atherogenic actions. The mechanisms responsible for these effects remain only partially elucidated. Diabetes and obesity are characterized by low-grade inflammation.
Mäuser, Wanda, Perwitz, Nina, Meier, Britta, Fasshauer, Mathias, Klein, Johannes   +4 more
core   +1 more source

Simultaneous Analysis of Antihyperlipidemic Drug Combinations by Green High‐Performance Liquid Chromatography Using Design of Experiments

SEPARATION SCIENCE PLUS, Volume 9, Issue 7, July 2026.
ABSTRACT Cardiovascular diseases are the leading cause of worldwide mortality, often supported by intricate dyslipidemic patterns of high levels of low‐density lipoprotein cholesterol and triacylglycerol. HMG‐CoA reductase inhibitors (statins) and ezetimibe can be used synergistically to treat these pathologies, as they target distinct metabolic ...
Venkatesh Bukkapatnam, Raja Sundararajan
wiley   +1 more source

[Atorvastatin in primary prevention]. [Birincil korunmada atorvastatin.]

, 2009
Statins are one of the most widely used drugs in medical treatment and have been shown to prevent cardiovascular disease or reduce risk in a large number of studies. Although there is a general class effect, there are differences with regard to structure
Kültürsay H.
core  

Effect of atorvastatin on energy metabolism of the blue mussels, Mytilus edulis

, 2019
Increasing concentration of biologically active pharmaceutical compounds can affect marine organisms. The bioavailability and environmental stability of these compounds make them potential threat to these organisms, specially the sessile organisms.
Sabrina Glufke (7884569), Udo Kragl (7884563), Stock, Marius, Falfushynska, Halina, Ruth, Wolfgang, Sokolova, Inna M, Fouzia Haider (7883918), Wolfgang Ruth (2325415), Oppermann, Christina, Eileen J Winkel (7884572), Glufke, Sabrina, Marius Stock (7884566), Inna M Sokolova (7398920), Christina Oppermann (7884560), Winkel, Eileen J, Kragl, Udo, Haider, Fouzia, Eugene P Sokolov (7884557), Halina Falfushynska (7398923), Sokolov, Eugene P   +19 more
core   +1 more source