Results 151 to 160 of about 56,049 (248)
Nilesh J Goswami,1 Mitch DeKoven,2 Andreas Kuznik,3 Jack Mardekian,3 Michelle R Krukas,2 Larry Z Liu,3,4 Patrick Bailey,1 Cynthia Deitrick,5 John Vincent3 1Prairie Heart Cardiovascular Consultants, Springfield, IL, USA; 2Health Economics and Outcomes ...
Deitrick C +8 more
core
Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients
Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen +14 more
wiley +1 more source
Background Coronary Slow Flow Phenomenon (CSFP) is a well-recognized clinical entity characterized by delayed opacification of coronary arteries in the presence of a normal coronary angiogram.
Nakisa Khansari +4 more
doaj +1 more source
ABSTRACT Background Cerebral cavernous malformations (CCM) are vascular lesions prone to hemorrhage, but the influence of modifiable cardiovascular risk factors and commonly prescribed therapies on bleeding risk remains unclear. Methods We performed a systematic review and meta‐analysis according to PRISMA 2020.
Sai Sanikommu +10 more
wiley +1 more source
Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella +2 more
wiley +1 more source
ABSTRACT Prompt diagnosis using CT is critical in gallstone ileus, as symptoms are often nonspecific. A combined surgical approach—comprising enterolithotomy, cholecystectomy, and fistula repair—effectively addresses both the obstruction and its underlying source, achieving favorable outcomes even in complex presentations.
Jiaxu Ji +3 more
wiley +1 more source
ABSTRACT Acute pancreatitis can present with ST‐segment elevation and marked troponin elevation, mimicking acute coronary syndrome. In resource‐limited settings where coronary angiography, cardiac magnetic resonance imaging, and serial high‐sensitivity troponin testing are unavailable, distinguishing acute myocardial injury associated with pancreatitis
Selamawit Kassahun Aweke +6 more
wiley +1 more source
Traditional &Kampo Medicine, Volume 13, Issue 3, December 2026.
Akiko Kikuchi +4 more
wiley +1 more source
Orforglipron is an orally administered, small‐molecule glucagon‐like peptide‐1 receptor agonist in clinical development for the treatment of type 2 diabetes and obesity. Orforglipron is a substrate of CYP3A4, organic anion transporting polypeptides (OATPs) 1B/1B3, and P‐glycoprotein (P‐gp); however, precipitants commonly used to define these mechanisms
Bridget L. Morse +7 more
wiley +1 more source
This graphical abstract illustrates the complete translational pipeline of Terminalia arjuna in modern phytomedicine and functional food development. It is rich in key bioactive compounds like arjunolic acid, arjungenin, flavonoids, and tannins which serve as the foundation for the plant's versatile medicinal uses and offers broad therapeutic benefits ...
Ishani Banerjee +5 more
wiley +1 more source

