Results 71 to 80 of about 55,917 (264)

Atorvastatin Induces Thrombomodulin Expression in the Aorta of Cholesterol -Fed Rabbits and in Tnf Alpha-Treated Human Aortic Endothelial Cells

, 2011
Expression of functionally active thrombomodulin (TM) on endothelial cells is critical for vascular thromboresistance . 3-Hydroxyl-3-methyl coenzyme A reductase inhibitors ( statins) can protect the vasculature from inflammation and atherosclerosis ...
林幸榮;謝芳瑜;陳永祥;林家齊;管奕奕;王淑慧;吳造中;簡雄飛;林豐彥;陳玉怜, LIN, SHING-JONG;HSIEH, FANG-YU;CHEN, YUNG-HSIANG;LIN, CHIA-CHI;KUAN, I-I;WANG, SHU-HUEI;WU, CHAU-CHUNG;CHIEN, HSIUNG-FEI;LIN, FENG-YEN;CHEN, YUH-LIEN   +1 more
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Estudo do efeito da atorvastatina sobre alterações comportamentais e bioquímicas em camundongos infundidos com o peptídeo ß-amilóide (Aß1-40) [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.A doença de Alzheimer (DA) é uma enfermidade neurológica que afeta grande parte da população mundial.
Martins, Wagner Carbolin
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Melanopsin‐Mediated Post‐Illumination Pupillary Response in Idiopathic Rapid Eye Movement (REM) Sleep Behavior Disorder and Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Aims To conduct a case–control study to investigate melanopsin‐mediated post‐illumination pupillary response (PIPR) in patients with Parkinson's disease (PD), video‐polysomnography‐confirmed isolated/idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD), and age‐matched healthy controls (HC). Methods PIPR was measured at 6 s after
Joey W.Y. Chan, Bei Huang, Siyi Gong, Yuhua Yang, Shi Tang, Steven Wai‐ho Chau, Ngan Yin Chan, Tim Man‐ho Li, Yaping Liu, Anne Y.Y. Chan, Karen K.Y. Ma, Shirley X. Li, Joshua Tsoh, Kelvin K.L. Chong, Kathryn A. Roecklein, Vincent C.T. Mok, Yun Kwok Wing   +16 more
wiley   +1 more source

Mechanism of inhibitory effect of atorvastatin on resistin expression induced by tumor necrosis factor-α in macrophages

Journal of Biomedical Science, 2009
Atorvastatin has been shown to reduce resistin expression in macrophages after pro-inflammatory stimulation. However, the mechanism of reducing resistin expression by atorvastatin is not known. Therefore, we sought to investigate the molecular mechanisms
Chua Su-Kiat, Shyu Kou-Gi, Wang Bao-Wai, Kuan Peiliang   +3 more
doaj   +1 more source

Porównanie intensywnego i standardowego obniżania stężenia lipidów za pomocą atorwastatyny u chorych z dyslipidemią cukrzycową Badanie DALI - podwójnie ślepa, randomizowana próba kliniczna kontrolowana placebo, przeprowadzona u chorych na cukrzycę typu 2 i dyslipidemię cukrzycową [PDF]

, 2002
INTRODUCTION. In patients with type 2 diabetes, intensive glucose regulation, although effective for microangiopathy, has not been shown to have unambiguous preventive effects on the occurrence of cardiovascular disease.
Intervention, Diabetes Atorvastatin Lipid
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Effects of atorvastatin and simvastatin on atrial plateau currents

, 2007
Recent evidence has shown that the inhibitors of the 3-hydroxy-3-methylglutaryl coenzyme A reductase (statins) might exert antiarrhythmic effects both in experimental models and in humans.
Vaquero González, Luis Miguel, Tamargo Menéndez, Juan, Delpón Mosquera, María Eva, Caballero Collado, Ricardo, Gómez García, Ricardo, Núñez Fernández, Lucía   +5 more
core   +1 more source

Advances in research on layered double hydroxides for biomedical applications

Smart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang, Zhiping Zhang, Zhao Wang, Hao Zhang, Yen Leng Pak, Yingying Jing, Yurong Guo, Fang Li, Xiao Wang, Quanxiang Han, Lei Yu, Xuejiao Li, Xing Gao, Jibin Song   +13 more
wiley   +1 more source

Dose-dependent effects of atorvastatin on myocardial infarction

, 2015
Olga Barbarash, Olga Gruzdeva, Evgenya Uchasova, Ekaterina Belik, Yulia Dyleva, Victoria KaretnikovaFederal State Budgetary Institution, Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, the Russian Federation Background ...
Dyleva Y, Uchasova E, Karetnikova V, Belik E, Barbarash O, Gruzdeva O   +5 more
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The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Atorvastatin Inhibits Inflammatory Response, Attenuates Lipid Deposition, and Improves the Stability of Vulnerable Atherosclerotic Plaques by Modulating Autophagy

Frontiers in Pharmacology, 2018
Atherosclerosis is a chronic disease comprising intima malfunction and arterial inflammation. Recent studies have demonstrated that autophagy could inhibit inflammatory response in atherosclerosis and exert subsequent atheroprotective effects.
Shi Peng, Long-Wei Xu, Xin-Yu Che, Qing-Qing Xiao, Jun Pu, Qin Shao, Ben He   +6 more
doaj   +1 more source