Results 101 to 110 of about 56,049 (248)

Impact of treatment with rosuvastatin and atorvastatin on cardiovascular outcomes: evidence from the Archimedes-simulated clinical trials

open access: yes, 2015
Furio Colivicchi,1 Catarina Sternhufvud,2 Sanjay K Gandhi3 1Cardiology Division, Emergency Department, San Filippo Neri Hospital, ASL Roma E, Rome, Italy; 2Global Payer Evidence and Pricing, AstraZeneca R&D, Mölndal, Sweden; 3Global Health ...
Colivicchi F, Sternhufvud C, Gandhi SK
core  

Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights

open access: yesBritish Journal of Pharmacology, EarlyView.
Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra   +5 more
wiley   +1 more source

Efficacy and Safety of Metformin and Atorvastatin Combination Therapy vs. Monotherapy with Either Drug in Type 2 Diabetes Mellitus and Dyslipidemia Patients (ATOMIC): Double-Blinded Randomized Controlled Trial [PDF]

open access: yesDiabetes & Metabolism Journal
Background It is well known that a large number of patients with diabetes also have dyslipidemia, which significantly increases the risk of cardiovascular disease (CVD). This study aimed to evaluate the efficacy and safety of combination drugs consisting
Jie-Eun Lee   +37 more
doaj   +1 more source

Voice Fundamental Frequency Variation and Statin Therapy

open access: yesClinical Otolaryngology, EarlyView.
ABSTRACT Objectives Statins are considered a first‐line treatment for dyslipidaemia, being the most frequently prescribed medicine worldwide. However, statin therapy has been associated with several adverse effects, including statin‐associated myopathy, which may manifest with symptoms such as myalgia, muscle stiffness, and cramps.
Luca Francesco Parata   +5 more
wiley   +1 more source

Efficacy of atorvastatin on the prevention of contrast-induced acute kidney injury: a meta-analysis

open access: yes, 2018
Ling-Yun Liu,1 Yang Liu,2 Mei-Yan Wu,2 Yan-Yan Sun,3 Fu-Zhe Ma2 1Department of Andrology, 2Department of Nephrology, the First Hospital of Jilin University, 3Department of Nephrology, the Fourth Hospital of Jilin University, Changchun, China Background:
Liu Y, Wu M, Liu L, Sun Y, Ma F
core  

Dyslipidaemia, Chronic Kidney Disease and Diabetes Mellitus: A Triple Threat to Cardiovascular Health

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Diabetes mellitus (DM) and chronic kidney disease (CKD) frequently coexist and together create a ‘triple threat’ with dyslipidaemia, enhancing the risk for cardiovascular morbidity and mortality. Diabetic kidney disease (DKD) leads to altered lipid metabolism through insulin resistance, inflammation and oxidative stress resulting in an ...
Ann S. Forrest   +3 more
wiley   +1 more source

In Vitro Blood-Brain-Barrier Permeability and Cytotoxicity of Atorvastatin-Loaded Nanoformulation Against Glioblastoma in 2D and 3D Models [PDF]

open access: yes, 2019
Inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase of the family of statins have been suggested as therapeutic options in various tumors.
Michael M, Lübtow   +14 more
core   +2 more sources

Gaps in diabetes care among people living with HIV and hypertension in Botswana: A cross‐sectional analysis of the InterCARE study

open access: yesHIV Medicine, EarlyView.
Abstract Objectives Data on diabetes screening and monitoring, within HIV care programmes in sub‐Saharan Africa, remain limited. This study describes the quality of diabetes screening and management among people living with HIV with comorbid hypertension receiving care at facilities participating in the InterCARE trial in Botswana. Methods We conducted
Onkabetse Julia Molefe‐Baikai   +15 more
wiley   +1 more source

Atorvastatin and cardiovascular risk in the elderly – patient considerations

open access: yes, 2008
Subroto Acharjee, Francine K WeltyDivision of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, USAAbstract: Elderly individuals are at increased risk of coronary heart disease (CHD) and account for a majority of CHD deaths.
Subroto Acharjee, Francine K Welty
core  

Comparison of pharmacogenomic guidance in Australian prescribing resources and international pharmacogenomic guidelines

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Pharmacogenomic‐guided medication management optimises drug therapy to enhance patient outcomes. Despite clinical utility, implementation in Australia remains limited, partly due to the lack of clear and consistent guidance. Aim This study evaluated the presence and consistency of pharmacogenomic testing indication categories and ...
Ruby Soueid   +4 more
wiley   +1 more source

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