Effects of atorvastatin on inflammatory markers, lipid profile, liver enzymes, and pulmonary function in patients with lung diseases: a systematic review and meta-analysis of randomized controlled trials. [PDF]
Baseri S +5 more
europepmc +1 more source
ABSTRACT Background According to global projections, by the year 2050, ischemic heart disease will remain the leading cause of cardiovascular deaths with hypertension as a leading modifiable risk factor for mortality. Improving quality care for patients with acute myocardial infarction (MI) is associated with improved outcomes. Aims There is inadequate
Banaz Sadiq Elias +2 more
wiley +1 more source
Atorvastatin Protects Against Deleterious Carfilzomib-Induced Transcriptional Changes in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. [PDF]
Tantawy M +9 more
europepmc +1 more source
Dermatomyositis Like Presentation of Anti‐HMGCR Immune Mediated Necrotising Myopathy
Capsule summary Cutaneous manifestations of HMGCR‐IMNM are rare and poorly described. Dermatomyositis‐like rash manifestation can be a presentation of the HMGCR‐IMNM. We report a case with a dermatomyositis‐like presentation and provide a literature review on this topic.
Lionel Leblanc +4 more
wiley +1 more source
Effects of rosuvastatin treatment and other statins on burn wound healing. [PDF]
Marneri AG +6 more
europepmc +1 more source
ABSTRACT Rosuvastatin (RVS) is an HMG‐CoA reductase inhibitor with lipid‐lowering properties. This study aims to investigate the role of RVS in plaque formation in atherosclerosis (AS) and its functional mechanism. ApoE−/− mice were fed a high‐fat diet to generate a mouse model of AS.
Xin Fu +5 more
wiley +1 more source
Biochemical urine analysis of atorvastatin and rosuvastatin by LC-MS: a pilot study of an objective method to assess non-adherence. [PDF]
Brockmeyer M +13 more
europepmc +1 more source
Severe Renal Phenotype Across A Multigenerational Tuberous Sclerosis Complex (TSC) Family
A five generation family with a known pathogenic variant (c.1372C>T; p.Arg458*) in TSC2 displaying a severe renal phenotype characterized by large angiomyolipomas, renal cystic disease, and chronic kidney disease leading to renal failure. Our report illustrates a possible genotype–phenotype and highlights the importance of establishing genotype ...
Elena Tuller +3 more
wiley +1 more source
LDL-C Goal Attainment with Fixed-Dose Ezetimibe and Atorvastatin Versus High-Dose Atorvastatin in Chinese Patients: Subgroup Analysis of a Randomized Trial. [PDF]
Qian J +8 more
europepmc +1 more source
Navigating the cholesterol maze: Key insights on use of statins in neurodegenerative disorders
The graphical abstract encapsulates the dual neuroprotective mechanisms of statins in neurodegenerative diseases, highlighting both cholesterol‐dependent and cholesterol‐independent pathways. By inhibiting 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase, statins reduce cholesterol synthesis, leading to altered lipid raft structures that ...
Jun Han Kuan +5 more
wiley +1 more source

