Estudo do efeito da atorvastatina sobre alterações comportamentais e bioquímicas em camundongos infundidos com o peptídeo ß-amilóide (Aß1-40) [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.A doença de Alzheimer (DA) é uma enfermidade neurológica que afeta grande parte da população mundial.
Martins, Wagner Carbolin
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Journal of Biomedical Science, 2009 Atorvastatin has been shown to reduce resistin expression in macrophages after pro-inflammatory stimulation. However, the mechanism of reducing resistin expression by atorvastatin is not known. Therefore, we sought to investigate the molecular mechanisms
Chua Su-Kiat +3 more
doaj +1 more source
Porównanie intensywnego i standardowego obniżania stężenia lipidów za pomocą atorwastatyny u chorych z dyslipidemią cukrzycową Badanie DALI - podwójnie ślepa, randomizowana próba kliniczna kontrolowana placebo, przeprowadzona u chorych na cukrzycę typu 2 i dyslipidemię cukrzycową [PDF]
, 2002 INTRODUCTION. In patients with type 2 diabetes, intensive glucose regulation, although effective for microangiopathy, has not been shown to have unambiguous preventive effects on the occurrence of cardiovascular disease.
Intervention, Diabetes Atorvastatin Lipid
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Effects of atorvastatin and simvastatin on atrial plateau currents
, 2007 Recent evidence has shown that the inhibitors of the 3-hydroxy-3-methylglutaryl coenzyme A reductase (statins) might exert antiarrhythmic effects both in experimental models and in humans.
Vaquero González, Luis Miguel +5 more
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Clinical Translation of Patient‐Derived Organoids: Perspectives for Personalized Therapy in Cancer
International Journal of Cancer, EarlyView.ABSTRACT Patient‐derived organoids (PDO) are accelerating precision medicine. These biological platforms allow for the autologous in vitro expansion of material from cancer patients in a considerably short period of time. These three‐dimensional models can faithfully recapitulate aspects of tissue heterogeneity, architecture, and relevant cellular ...
Haiyan Yue +6 more
wiley +1 more source
Dose-dependent effects of atorvastatin on myocardial infarction
, 2015 Olga Barbarash, Olga Gruzdeva, Evgenya Uchasova, Ekaterina Belik, Yulia Dyleva, Victoria KaretnikovaFederal State Budgetary Institution, Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, the Russian Federation Background ...
Dyleva Y +5 more
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Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis
iNew Medicine, EarlyView.This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang +3 more
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Pharmacokinetic interaction between fimasartan and atorvastatin in healthy male volunteers
, 2018 Yewon Choi, SeungHwan Lee, In-Jin Jang, Kyung-Sang Yu Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea Introduction: Major cardiovascular risk factors, including ...
Lee S, Jang IJ, Yu KS, Choi Y
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A comparative study of efficacy of atorvastatin, rosuvastatin, and atorvastatin + fibrates as lipid lowering agents [PDF]
, 2017 Background: Hypercholesterolemia patients are at high risk of coronary heart disease. National cholesterol education programme (NCEP) Adult Treatment Panel III guidelines provide the option of aggressively lowering Low-density cholesterol in them ...
Vadlamannati, Yamini +2 more
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Atorvastatin ascorbic acid cocrystal strategy to improve the safety and efficacy of atorvastatin
, 2022 The study was aimed to investigate the effect of dissolution enhancement on the hypolipidemic effect and hepatotoxicity of the drug in hyperlipidemic rats. Atorvastatin ascorbic acid cocrystals were prepared by phase solution methods and characterized by
Laddha, Umesh D. +13 more
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