Results 111 to 120 of about 3,667 (197)

Pharmacokinetics and dynamics of atovaquone and proguanil (Malarone®) [Elektronisk resurs]

, 2004
Malarone® is a fixed dose combination of atovaquone and proguanil and is mainly used for prophylaxis against P. falciparum malaria as an alternative to Lariamo® or chloroquine+proguanil.
Thapar, MM,
core  

Short report: no evidence of cardiotoxicity of atovaquone-proguanil alone or in combination with artesunate.

, 2005
Combinations are set to become the mainstay in treatment and prophylaxis of malaria due to Plasmodium falciparum. Various antimalarials have been implicated in cardiotoxicity via prolongation of the QTc interval.
Gupta, Ravindra K., Looareesuwan, S, White, Nicholas J., Van Vugt, M, Looareesuwan, Sornchai, Gupta, RK, van Vugt, Michele, Paiphun, Lucy, Slight, T, Slight, Thra, White, NJ, White, Nicholas, Nosten, F, Paiphun, L, Nosten, François   +14 more
core  

Atovaquone-proguanil exposure in pregnancy and risk for adverse fetal and infant outcomes: A retrospective analysis. [PDF]

Travel Med Infect Dis, 2019
Gutman JR, Hall C, Khodr ZG, Bukowinski AT, Gumbs GR, Conlin AMS, Wells NY, Tan KR.   +7 more
europepmc   +1 more source

The safety of atovaquone-proguanil for the prevention and treatment of malaria in pregnancy: A systematic review. [PDF]

Travel Med Infect Dis, 2019
Andrejko KL, Mayer RC, Kovacs S, Slutsker E, Bartlett E, Tan KR, Gutman JR.   +6 more
europepmc   +1 more source

Atovaquone/proguanil-induced autoimmune-like hepatitis. [PDF]

Hepatol Commun, 2017
Terziroli Beretta-Piccoli B, Mieli-Vergani G, Bertoli R, Mazzucchelli L, Nofziger C, Paulmichl M, Vergani D.   +6 more
europepmc   +1 more source

A randomized, open-label two-period crossover pilot study to evaluate the relative bioavailability in the fed state of atovaquone-proguanil (Atoguanil™) versus atovaquone-proguanil hydrochloride (Malarone®) in healthy adult participants. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Kuemmerle A, Gossen D, Marx MW, Lorch U, Szramowska M, Kumar A, Singh D, Singh S, Ramachandruni H, Thankachen B, Kore S, Gaaloul ME, Borghini-Fuhrer I, Chalon S.   +13 more
europepmc   +1 more source

Acute malaria infection after atovaquone-proguanil prophylaxis. [PDF]

J Travel Med, 2017
Minta AA, Tan KR, Mace KE, Arguin PM.
europepmc   +1 more source

Superior protection in a relapsing Plasmodium cynomolgi rhesus macaque model by a chemoprophylaxis with sporozoite immunization regimen with atovaquone-proguanil followed by primaquine. [PDF]

Malar J
Yongvanitchit K, Kum-Arb U, Limsalakpetch A, Im-Erbsin R, Ubalee R, Spring MD, Vesely BA, Waters N, Pichyangkul S.   +8 more
europepmc   +1 more source

Atovaquone-Proguanil in Combination With Artesunate to Treat Multidrug-Resistant P. falciparum Malaria in Cambodia: An Open-Label Randomized Trial. [PDF]

Open Forum Infect Dis, 2019
Wojnarski M, Lon C, Vanachayangkul P, Gosi P, Sok S, Rachmat A, Harrison D, Berjohn CM, Spring M, Chaoratanakawee S, Ittiverakul M, Buathong N, Chann S, Wongarunkochakorn S, Waltmann A, Kuntawunginn W, Fukuda MM, Burkly H, Heang V, Heng TK, Kong N, Boonchan T, Chum B, Smith P, Vaughn A, Prom S, Lin J, Lek D, Saunders D.   +28 more
europepmc   +1 more source

Atovaquone/Proguanil Therapy for \u3ci\u3ePlasmodium falciparum\u3c/i\u3e and \u3ci\u3ePlasmodium vivax\u3c/i\u3e Malaria in Indonesians Who Lack Clinical Immunity

, 2002
Thirty-eight of 295 subjects participating in a randomized, double-blind, placebo-controlled trial of the efficacy of daily administration of atovaquone/proguanil for malaria prevention developed malaria at some time during the 20-week prophylaxis period.
Barcus, Mazie J., Miller, Gerri B., Ling, Judith, Baird, J. Kevin, Basri, Hasan, Hoffman, Stephen L., Bangs, Michael J., Sismadi, Priyanto, Chulay, Jeffrey D., Gramzinski, Robert, Lacy, Mark D., Maguire, Jason D., Fryauff, David J.   +12 more
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