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Atovaquone—Proguanil Combination
2001Development of an atovaquone—proguanil combination, trademarked Malarone, during the 1990s has been a major step in addressing the need for antimalarial drugs with targets different from those of agents for which resistance is already rampant in the field (1).
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▼Atovaquone + proguanil for malaria prophylaxis
Drug and Therapeutics Bulletin, 2001▼Atovaquone + proguanil* (Malarone - GlaxoSmithKline) is a fixed-dose combination of two antiparasitic drugs. In 1996, it was licensed in the UK for the treatment of acute, uncomplicated falciparum malaria. Earlier this year, the combination was licensed additionally for prophylaxis of falciparum malaria.
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