Results 11 to 20 of about 84,320 (339)
Chalcone Derivatives Enhance ATP-Binding Cassette Transporters A1 in Human THP-1 Macrophages [PDF]
Atherosclerosis is a process of imbalanced lipid metabolism in the vascular walls. The underlying pathology mainly involves the deposition of oxidized lipids in the endothelium and the accumulation of cholesterol in macrophages.
I-Jou Teng +8 more
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Cadmium transport by mammalian ATP-binding cassette transporters. [PDF]
AbstractCellular responses to toxic metals depend on metal accessibility to intracellular targets, reaching interaction sites, and the intracellular metal concentration, which is mainly determined by uptake pathways, binding/sequestration and efflux pathways.
Thévenod F, Lee WK.
europepmc +4 more sources
Thermodynamics of the ATPase Cycle of GlcV, the Nucleotide-Binding Domain of the Glucose ABC Transporter of Sulfolobus solfataricus [PDF]
ATP-binding cassette transporters drive the transport of substrates across the membrane by the hydrolysis of ATP. They typically have a conserved domain structure with two membrane-spanning domains that form the transport channel and two cytosolic ...
Albers, Sonja-Verena, +5 more
core +14 more sources
Keypoints P. aromaticivorans AR20-38 differentially regulates three main enzymes for the bioconversion of ferulic acid to vanillic acid. ATP binding cassette transporters, major facilitator superfamily transporters and outer membrane vesicles are ...
Caroline Poyntner +3 more
doaj +1 more source
Chemoradiotherapy is frequently used to treat cancer. Stereotactic body radiotherapy (SBRT) is a single high-dose radiotherapy used to treat a variety of cancers.
Kakeru Sato +12 more
doaj +1 more source
ECF-Type ATP-Binding Cassette Transporters [PDF]
Energy-coupling factor (ECF)–type ATP-binding cassette (ABC) transporters catalyze membrane transport of micronutrients in prokaryotes. Crystal structures and biochemical characterization have revealed that ECF transporters are mechanistically distinct from other ABC transport systems.
Rempel, S, Stanek, W K, Slotboom, D J
openaire +2 more sources
ATP-binding cassette (ABC) transporters constitute the largest family of primary active transporters involved in a multitude of physiological processes and human diseases.
Erich Stefan +7 more
doaj +1 more source
Hsa_Circ_0007841 Enhances Multiple Myeloma Chemotherapy Resistance Through Upregulating ABCG2
The current researches have reported that circular RNA is an important regulatory factor in the progression of various human disease. However, the function and mechanism of most circular RNAs remain unknown in cancers including multiple myeloma.
Yan Song MD +3 more
doaj +1 more source
Cisplatin is one of the first line anti-cancer drugs prescribed for treatment of solid tumors; however, the chemotherapeutic drug resistance is still a major obstacle of cisplatin in treating cancers. Yu Ping Feng San (YPFS), a well-known ancient Chinese
Yingqing Du +19 more
doaj +1 more source
ATP‐binding cassette transporters in nonmodel plants [PDF]
SummaryKnowledge about plant ATP‐binding cassette (ABC) proteins is of great value for sustainable agriculture, economic yield, and the generation of high‐quality products, especially under unfavorable growth conditions. We have learned much about ABC proteins in model organisms, notably Arabidopsis thaliana; however, the importance of research ...
Joanna Banasiak, Michał Jasiński
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