Results 311 to 320 of about 156,745 (364)
Oxidative Stress in HIV Infection and Alcohol Use: Role of Redox Signals in Modulation of Lipid Rafts and ATP-Binding Cassette Transporters. [PDF]
Antioxid Redox Signal, 2018 Thangavel S +6 more
europepmc +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich +9 more
wiley +1 more source
Arabidopsis PEN3/PDR8, an ATP binding cassette transporter, contributes to nonhost resistance to inappropriate pathogens that enter by direct penetration [PDF]
, 2006 Dittgen, J. +7 more
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend During development, Intersectin‐1 (Itsn1) translocates near voltage‐gated calcium channels (VGCCs) to enhance Ca2+‐dependent replenishment of readily releasable synaptic vesicles (SVs). In the presynaptic terminal, SVs undergo a cycle involving formation (step 1), docking (step 2), exocytosis (step 3), endocytosis (step 4) and ...
Yi‐Mei Yang +13 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Human intestinal organoids were genetically modified to express a fluorescent protein in enteroendocrine cells (EECs), which were then separated by flow cytometry and analysed by single‐cell RNA sequencing. High numbers of human EECs were thereby available for cluster analysis and differential gene expression, revealing ...
Christopher A. Smith +7 more
wiley +1 more source
GATA Transcription Factors: A Cross‐Road for Erythropoiesis, Neurodevelopment, and Synucleinopathies
Developmental Neurobiology, Volume 85, Issue 3, July 2025.ABSTRACT Alpha‐synuclein (α‐syn), a 140 amino acid protein, is abundantly expressed in the central nervous system (CNS) and in the erythrocytes, playing a pivotal role in the pathogenesis of Parkinson's disease (PD) and other synucleinopathies.
Francesco Bellomi +7 more
wiley +1 more source
HB52‐PUT2 Module‐Mediated Polyamine Shoot‐to‐Root Movement Regulates Salt Stress Tolerance in Tomato
Plant, Cell &Environment, Volume 48, Issue 7, Page 5148-5163, July 2025.ABSTRACT Soil salinity severely restricts crop quality and yields. Plants have developed various strategies to alleviate salinity stress's negative effects, including polyamine redistribution by polyamine uptake transporters (PUTs). However, the mechanisms by which PUTs alter polyamine translocation processes during salt stress have not been fully ...
Xian Yang +7 more
wiley +1 more source
Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung Microbiota
Angewandte Chemie, Volume 137, Issue 24, June 10, 2025.Genome mining of environmental and pathogenic Pandoraea species identified a conserved NRPS gene cluster and led to the discovery of novel siderophores, pandorabactins, which exert their antibacterial activity by depleting iron from competitors. Bioinformatic analysis of sputum from cystic fibrosis patients coupled with bioassays indicates that ...
Elena Herzog +8 more
wiley +2 more sources
Plant, Cell &Environment, Volume 48, Issue 7, Page 5271-5289, July 2025.ABSTRACT The smut fungus Sporisorium scitamineum is a major pathogen in sugarcane, causing significant agricultural losses worldwide. However, the molecular mechanisms by which its effectors facilitate infection and evade host immunity remain largely unclear.
Hui Ling +6 more
wiley +1 more source