Results 101 to 110 of about 1,799,367 (292)

Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves, Darius Lane, Adam Wahida, Md. Jakaria, Pawel Kalinowski, Adam Southon, Abdel Ali Belaidi, Teresa Samperi‐Esteve, Triet Phu Minh Nguyen, Peng Lei, Marcus Krueger, Stefan Mueller, Marcus Conrad, Puja Agarwal, Sue E Leurgans, Julie Schneider, Ashley I. Bush, Scott Ayton   +17 more
wiley   +1 more source

Maximizing efficiency of rumen microbial protein production. [PDF]

, 2015
Rumen microbes produce cellular protein inefficiently partly because they do not direct all ATP toward growth. They direct some ATP toward maintenance functions, as long-recognized, but they also direct ATP toward reserve carbohydrate synthesis and ...
Andries, Argyle, Armstead, Asanuma, Asanuma, Atasoglu, Atasoglu, Atasoglu, Bailey, Bailey, Baldwin, Baldwin, Bas, Bond, Bond, Bond, Buurman, Caldara, Chen, Cheng, Clapperton, Clark, Cook, Costerton, Cotta, Cotta, Counotte, Denton, Diaz, Diez-Gonzalez, Dijkstra, Dijkstra, Dijkstra, Duncan, Dunne, Falony, Ferla, Fields, Firkins, Firkins, Firkins, Firkins, Flint, Forsberg, Gaudet, Gottschalk, Hackmann, Hackmann, Hackmann, Hall, Hanigan, Hindson, Hino, Hobson, Hobson, Hottiger, Hristov, Hristov, Isaacson, Janssen, Jenkins, Jouany, Kajikawa, Kajikawa, Kajikawa, Kalcheva, Karnati, Kim, Koenig, Krause, Kristensen, Larsson, Leedle, Lohkamp, Lou, Lou, Lou, Louis, Mackie, Maia, Martin, Matheron, Matulova, McAllan, Morgan, Morgavi, Morrison, Morrison, Mountfort, Mouriño, Mulder, Nagaraja, Neijssel, Newbold, Newsholme, Newsholme, Nouaille, NRC., Oldick, Or-Rashid, Otto, Paillard, Paulus, Pirt, Piwonka, Portais, Prabhu, Preiss, Prins, Rosewarne, Russell, Russell, Russell, Russell, Russell, Russell, Russell, Russell, Russell, Russell, Russell, Russell, Russell, Ryan, Saleem, Schönheit, Shi, Shi, Stewart, Storm, Stouthamer, Suen, Teixeira de Mattos, Tempest, Tempest, Ungerfeld, van Hijum, Van Hoven, Van Kessel, Van Kessel, Van Soest, Van Urk, Vandehaar, Walker, Wallace, Wallace, Wang, Weimer, Weimer, Weimer, Wells, Wells, White, Wilkinson, Williams, Williams, Yang, Ze, Zhou   +158 more
core   +2 more sources

ATP inhibits the spontaneous contractility of atria in rats

Учёные записки Казанского университета: Серия Естественные науки, 2018
ATP is a multifunctional nucleotide. In recent years, strong evidence has accumulated that ATP may participate in intercellular signaling, where ATP acts as a cotransmitter.
A.A. Zverev, T.A. Anikina, N.G. Iskakov, N.V. Leonov, T.L. Zefirov   +4 more
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Fondová schémata jako možná řešení finanční udržitelnosti dánského penzijního systému

Trendy v podnikání, 2020
The financial sustainability of pension systems is one of the crucial topics in the context of population aging. The issue of financial sustainability is primarily associated with public unfunded pension schemes, where there is an increase in future ...
Jan Pokorný, Pavlína Hejduková
doaj   +1 more source

Novel Anthraquinone Chlorination Contributes to Pigmentation and ATP Formation in Thermomyces dupontii

Microbial Biotechnology, Volume 18, Issue 10, October 2025.
This diagram illustrates the chlorination of anthraquinones and its biological functions in Thermomyces dupontii, elucidating how chlorination‐mediated fungal pigmentation promotes energy production and stress adaptation. (1) Extracellular Fenton Chemistry: Involves superoxide anion (O2−) and ferrous ion (Fe2+), which are two fundamental elements for ...
Donglou Wang, Gang Dai, Jiangbo He, Huiwen Si, Chunhua Liao, Wenjie Wang, Zhangxin Zuo, Shuhong Li, Xuemei Niu   +8 more
wiley   +1 more source

A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP

Nature Communications, 2018
Adenosine 5′ triphosphate (ATP) is a universal intracellular energy source and an evolutionarily ancient, ubiquitous extracellular signal in diverse species.
M. A. Lobas, Rongkun Tao, J. Nagai, Mira T. Kronschläger, P. Borden, J. Marvin, L. Looger, B. Khakh   +7 more
semanticscholar   +1 more source

Presynaptic ATP Decreases During Physiological‐Like Activity in Neurons Tuned for High‐Frequency Transmission

Journal of Neurochemistry, Volume 169, Issue 9, September 2025.
We mainly used mice to express a FRET‐based ATP sensor in a subset of cerebellar mossy fibers. In acute brain slices, two‐photon FRET measurements at presynaptic cerebellar mossy fiber boutons were performed. Physiological‐like stimulation elicited a decrease in the presynaptic ATP concentration.
Isabelle Straub, Lukas Kunstmann, Felipe Baeza‐Lehnert, Saad Chowdhry, Robert B. Renden, Gerardo Gonzalez‐Aragón, Bernhard Groschup, Thomas Hofmann, Saša Jovanović, Mandy Sonntag, Daniel Gitler, Michael Schaefer, Jens Eilers, L. Felipe Barros, Johannes Hirrlinger, Stefan Hallermann   +15 more
wiley   +1 more source

Differential sensitivity of brainstem vs cortical astrocytes to changes in pH reveals functional regional specialization of astroglia [PDF]

, 2013
Astrocytes might function as brain interoceptors capable of detecting different (chemo)sensory modalities and transmitting sensory information to the relevant neural networks controlling vital functions.
Castaldo, C, Gourine, A, Kasimov, V, Kasparov, Sergey, Larina, O, Marina, N, Patrushev, M   +6 more
core   +2 more sources

Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

Nature Communications, 2018
Adenosine triphosphate (ATP) plays fundamental roles in cellular biochemistry and was recently discovered to function as a biological hydrotrope. Here, we use mass spectrometry to interrogate ATP-mediated regulation of protein thermal stability and ...
Sindhuja Sridharan, N. Kurzawa, Thilo Werner, Ina Günthner, D. Helm, W. Huber, M. Bantscheff, M. Savitski   +7 more
semanticscholar   +1 more source

Saturação de creatina em indivíduos fisicamente ativos: técnica eficaz ou desnecessária?

Revista Brasileira de Nutrição Esportiva, 2016
A creatina é um nutriente natural, de procedência animal encontrada em carnes vermelhas e peixes. É um suplemento que vem sendo estudado desde a década de 90, onde foi notado seu uso frequente por atletas de elite nas olimpíadas de Barcelona em 1992.
Luiz Eduardo Marinho Falcão
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