Results 261 to 270 of about 60,219 (305)

Valproate reactivates HTLV-1 tax and reduces ABCB1/MDR1 expression in PBMCs derived from ATLL patients. [PDF]

Front Oncol
Mourouvin C, Tram J, Marty L, Marie-Delcasse A, Belrose G, Pluta A, Césaire R, Hélias P, Baccini V, Peloponese JM.   +9 more
europepmc   +1 more source

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ATP-binding cassette transporter 1 C69T and V825I polymorphisms in the development of atherosclerosis: A meta-analysis of 18,320 subjects

Thrombosis Research, 2015
ATP-binding cassette transporter 1 (ABCA1), a member of the ATP-binding cassette family, plays a critical role in the development of atherosclerosis (AS). This meta-analysis was performed to assess the associations of ABCA1 C69T and V825I polymorphisms with AS susceptibility.A comprehensive search was conducted to identify all eligible studies from ...
Yan-Wei Yin, Qian-Qian Sun, Ai-Min Hu
exaly   +3 more sources

ATP-Binding Cassette Transporter C4 is a Prostaglandin D2 Exporter in HMC-1 cells

Prostaglandins, Leukotrienes and Essential Fatty Acids, 2020
ATP-binding cassette transporter C4 (ABCC4) is associated with multidrug resistance and the regulation of cell signalling. Some prostaglandins (PGs), including: PGE2, PGF2α, PGE3, and PGF3α are known substrates of ABCC4, and are released from some types of cells to exert their biological effects.
Nobuaki, Tanaka, Junya, Kawai, Noriyasu, Hirasawa, Nariyasu, Mano, Hiroaki, Yamaguchi   +4 more
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The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

Nature Genetics, 1999
Tangier disease (TD) is an autosomal recessive disorder of lipid metabolism. It is characterized by absence of plasma high-density lipoprotein (HDL) and deposition of cholesteryl esters in the reticulo-endothelial system with splenomegaly and enlargement of tonsils and lymph nodes.
M, Bodzioch, E, Orsó, J, Klucken, T, Langmann, A, Böttcher, W, Diederich, W, Drobnik, S, Barlage, C, Büchler, M, Porsch-Ozcürümez, W E, Kaminski, H W, Hahmann, K, Oette, G, Rothe, C, Aslanidis, K J, Lackner, G, Schmitz   +16 more
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Interaction of angiotensin receptor type 1 blockers with ATP‐binding cassette transporters

Biopharmaceutics & Drug Disposition, 2010
AbstractATP‐binding cassette (ABC)‐transporters, such as P‐glycoprotein (P‐gp/ABCB1), multidrug resistance‐associated proteins (MRPs/ABCCs) and breast cancer resistance protein (BCRP/ABCG2) transport numerous drugs thus regulating their absorption, distribution and excretion.
J, Weiss, A, Sauer, N, Divac, M, Herzog, E, Schwedhelm, R H, Böger, W E, Haefeli, R A, Benndorf   +7 more
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Structural snapshot of the cholesterol-transport ATP-binding cassette proteins 1.

Biochemistry and cell biology = Biochimie et biologie cellulaire, 2019
The ATP-binding cassette (ABC) proteins play critical roles in maintaining lipid and sterol homeostasis in higher eukaryotes. In humans, several subfamily-A and -G members function as cholesterol transporters across the cellular membranes. Deficiencies of these ABC proteins can cause dyslipidemia that is associated with health conditions such as ...
Bala M, Xavier, William J, Jennings, Aiman A, Zein, Junmei, Wang, Jyh-Yeuan, Lee   +4 more
openaire   +2 more sources

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

Nature Genetics, 1999
Tangier disease (TD) was first discovered nearly 40 years ago in two siblings living on Tangier Island. This autosomal co-dominant condition is characterized in the homozygous state by the absence of HDL-cholesterol (HDL-C) from plasma, hepatosplenomegaly, peripheral neuropathy and frequently premature coronary artery disease (CAD).
S, Rust, M, Rosier, H, Funke, J, Real, Z, Amoura, J C, Piette, J F, Deleuze, H B, Brewer, N, Duverger, P, Denèfle, G, Assmann   +10 more
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Expression of ATP-binding cassette membrane transporters in a HIV-1 transgenic rat model

Biochemical and Biophysical Research Communications, 2014
P-glycoprotein (P-gp, product of Mdr1a and Mdr1b genes), multidrug resistance associated proteins (Mrps), and breast cancer resistance protein (Bcrp), all members of the ATP-binding cassette (ABC) membrane-associated drug transporters superfamily, can significantly restrict the entry of antiretroviral drugs (ARVs) into organs which exhibit a barrier ...
Kevin R, Robillard, Md Tozammel, Hoque, Reina, Bendayan   +2 more
openaire   +2 more sources