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Common Variants in the ATP-binding Cassette Transporter 1 Gene with Decreased HDL-Cholesterol Levels and Coronary Artery Disease

Archives of Medical Research, 2008
Our aim was to determine whether the common variants within the coding sequence of ABCA1 gene affects low plasma high-density lipoprotein cholesterol (HDL-C) levels in Turkish patients with coronary artery disease (CAD). The study group was composed of 552 CAD patients, of which 251 had HDL-C levels < or =40 mg/dL, and 301 had HDL-C levels >40 mg/dL ...
Alp Burak, Catakoglu   +8 more
openaire   +4 more sources

[Relationship between ATP-binding cassette transporter 1 R219K genetic variation and blood lipids].

Zhonghua yi xue za zhi, 2005
To investigate whether ATP-binding cassette transporter 1 (ABCA1) R219K genetic variation is correlated with blood lipids.Specimens of peripheral blood were collected from 692 patients with cerebral apoplexy, aged 62 +/- aged 12, and 352 sex- and age-matched persons without cardio-cerebro-vascular disease. Polymerase chain reaction-restricted fragments
Shui-Ping, Zhao   +6 more
openaire   +1 more source

Midkine Promote Atherosclerosis by Regulating the Expression of ATP-Binding Cassette Transporter A1 via Activator Protein-1

Cardiovascular Drugs and Therapy
Midkine (MK) has been shown to facilitate atherosclerotic plaque formation by downregulating the expression of ATP-binding cassette transporter A1 (ABCA1). However, the mechanism by which MK regulates ABCA1 to promote atherosclerosis remains incompletely understood.
Yixin Tang   +4 more
openaire   +2 more sources

[Relationship between the R219K polymorphism of ATP-binding cassette transporter 1 gene and coronary heart disease].

Yi chuan = Hereditas, 2008
To study the distribution of R219K polymorphism in ATP-Binding Cassette Transporter 1 (ABCA1) gene in Chinese Han population and the association of this polymorphism with coronary heart disease (CHD) . Genotypes were determined by PCR-RFLP approach in 417 unrelated healthy controls and 396 CHD patients.
Ya, Li   +7 more
openaire   +1 more source

Effect of the interaction between paranoxonase 1 and ATP-binding cassette transporter 1 gene polymorphism on serum lipid level.

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2009
To investigate the effect of interaction between paranoxonase 1 (PON1)gene polymorphism and ATP-binding cassette transporter 1 (ABCA1) genetic variation on serum lipid level.Polymerase chain reaction-restricted fragments length polymorphism was used to determine PON1 A/B192 and ABCA1R219K genotype of 1019 subjects, including 680 patients with strokes ...
Zhi-jie, Xiao   +6 more
openaire   +1 more source

The human ATP‐binding cassette (ABC) transporter superfamily

Human Mutation, 2022
Michael Dean   +2 more
exaly  

The expression of human ATP-binding cassette transporter 1 mRNA increased by oxidized LDL

Atherosclerosis, 2000
Y Wanaka   +5 more
openaire   +1 more source

Palmitoylation of ATP-Binding Cassette Transporter A1 Is Essential for Its Trafficking and Function

Circulation Research, 2009
Roshni R Singaraja   +2 more
exaly  

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