Results 141 to 150 of about 40,880 (280)

Targeting mitochondrial 18 kDa translocator protein (TSPO) regulates macrophage cholesterol efflux and lipid phenotype [PDF]

, 2014
The aim of the present study was to establish mitochondrial cholesterol trafficking 18 kDa translocator protein (TSPO) as a potential therapeutic target, capable of increasing macrophage cholesterol efflux to (apo)lipoprotein acceptors.
Anne-Marie Allen, Annette Graham, Batarseh, Bird, Borthwick, Borthwick, Brown, Dmitrova-Shumkovska, Engel, Falchi, Farke, Feramisco, Fernandez-Hernando, Gallus, Gerrity, Gut, Hebbachi, Janice M. W. Taylor, Kannel, Khan, Lecanu, Madamanchi, Mercer, Ning, Ning, Ogata, Oram, Pandak, Puddu, Pyper, Rae, Ren, Rigamonti, Rone, Rosenson-Schloss, Rupprecht, Schnoor, Schultz, Taylor, Vanhee, Venkateswaran, Wang, Xu, Yelieev, Zeng, Zeng, Zoltan   +46 more
core   +1 more source

Photobiomodulation therapy promotes the ATP-binding cassette transporter A1-dependent cholesterol efflux in macrophage to ameliorate atherosclerosis. [PDF]

J Cell Mol Med, 2021
Yin Q, Chang H, Shen Q, Xing D.
europepmc   +1 more source

Expresión diferencial de genes en Pyropia columbina (Bangiales, Rhodophyta) bajo hidratación y desecación natural [PDF]

, 2013
Indexación: Web of Science; Scielo.RESUMEN. En Zonas Costeras rocosas, la desecación es gatillada porción Cambios Diarios en los Niveles de marea, y la Evidencia indica experimental de Me Distribución de las algas en la zona intermareal no está ...
Contreras-Porcia, Loretto, Correa, Juan A., Fierro, Camila, Flores-Molina, María Rosa, Guajardo, Eduardo, Kube, Michael, Lovazzano, Carlos, López-Cristoffanini, Camilo, Núñez, Alejandra, Reinhardt, Richard, Thomas, Daniela   +10 more
core  

New perspectives in signaling mediated by receptors coupled to stimulatory G protein: the emerging significance of cAMP efflux and extracellular cAMP-adenosine pathway [PDF]

, 2015
G protein coupled receptors (GPCRs) linked to stimulatory G (Gs) proteins (GsPCRs) mediate increases in intracellular cyclic AMP as consequence of activation of nine adenylyl cyclases, which differ considerably in their cellular distribution and ...
Duarte, Thiago, Godinho, Rosely Oliveira, Pacini, Enio Setsuo Arakaki   +2 more
core   +2 more sources

Astaxanthin Enhances ATP-Binding Cassette Transporter A1/G1 Expressions and Cholesterol Efflux from Macrophages

Journal of Nutritional Science and Vitaminology, 2012
ATP-binding cassette transporters (ABC) A1 and G1 are key molecules in cholesterol efflux from macrophages, which is an initial step of reverse cholesterol transport (RCT), a major anti-atherogenic property of high-density lipoprotein (HDL). Astaxanthin is one of the naturally occurring carotenoids responsible for the pink-red pigmentation in a variety
Maki, Iizuka, Makoto, Ayaori, Harumi, Uto-Kondo, Emi, Yakushiji, Shunichi, Takiguchi, Kazuhiro, Nakaya, Tetsuya, Hisada, Makoto, Sasaki, Tomohiro, Komatsu, Makiko, Yogo, Yoshimi, Kishimoto, Kazuo, Kondo, Katsunori, Ikewaki   +12 more
openaire   +3 more sources

ABCA1 promotes the efflux of bacterial LPS from macrophages and accelerates recovery from LPS-induced tolerance[S]

Journal of Lipid Research, 2010
Macrophages play important roles in both lipid metabolism and innate immunity. We show here that macrophage ATP-binding cassette transporter A1 (ABCA1), a transporter known for its ability to promote apolipoprotein-dependent cholesterol efflux, also ...
Patricia A. Thompson, Karine C. Gauthier, Alan W. Varley, Richard L. Kitchens   +3 more
doaj   +1 more source

POS0343 STATINS INFLUENCE THE RELATIONSHIP BETWEEN ATP-BINDING CASSETTE TRANSPORTER A1 (ABCA1)-MEDIATED CHOLESTEROL EFFLUX AND CORONARY ATHEROSCLEROSIS IN RHEUMATOID ARTHRITIS [PDF]

, 2023
George Karpouzas, Bianca Papotti, Sarah R. Ormseth, Marcella Palumbo, Elizabeth Hernández, Maria Pia Adorni, Francesca Zimetti, Matthew J. Budoff, Nicoletta Ronda   +8 more
openalex   +1 more source

Lipid efflux in human and mouse macrophagic cells: evidence for differential regulation of phospholipid and cholesterol efflux

Journal of Lipid Research, 2005
ABCA1 is a critical regulator of lipid efflux from cells, which is highly regulated at the transcriptional and posttranslational levels. However, cells from different species and different tissues, and primary versus immortalized cells, show different ...
Robert S. Kiss, Jovana Maric, Yves L. Marcel   +2 more
doaj   +1 more source

Physiologically regulated transgenic ABCA1 does not reduce amyloid burden or amyloid-β peptide levels in vivo

Journal of Lipid Research, 2007
ABCA1-deficient mice have low levels of poorly lipidated apolipoprotein E (apoE) and exhibit increased amyloid load. To test whether excess ABCA1 protects from amyloid deposition, we crossed APP/PS1 mice to ABCA1 bacterial artificial chromosome (BAC ...
Veronica Hirsch-Reinshagen, Jennifer Y. Chan, Anna Wilkinson, Tracie Tanaka, Jianjia Fan, George Ou, Luis F. Maia, Roshni R. Singaraja, Michael R. Hayden, Cheryl L. Wellington   +9 more
doaj   +1 more source

Assessment of genetic polymorphism associated with ATP-binding cassette transporter A1 (ABCA1) gene and fluctuations in serum lipid profile levels in patients with coronary artery disease. [PDF]

Saudi Pharm J, 2021
Bogari NM, Babalghith AO, Bouazzaoui A, Aljohani A, Dannoun A, Elkhateeb O, Amin AA, Bogari MK, Mazhar AA, Porqueddu M, Khan IA.   +10 more
europepmc   +1 more source