Assessment of genetic polymorphism associated with ATP-binding cassette transporter A1 (ABCA1) gene and fluctuations in serum lipid profile levels in patients with coronary artery disease. [PDF]
Bogari NM +10 more
europepmc +1 more source
Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages. [PDF]
Activation of liver X receptors (LXRs) with synthetic agonists promotes reverse cholesterol transport and protects against atherosclerosis in mouse models.
Bahadorani, John +16 more
core +1 more source
Vincent V, Thakkar H, Aggarwal S, et al. Diabetes Metab Syndr Obes. 2019:12;275–284.On page 283, the Acknowledgements section should be presented as follows: The authors would like to acknowledge Dr Manjunath Maruti Pol, Dr ...
Vincent V +5 more
doaj
ABCA1-deficient mice have low levels of poorly lipidated apolipoprotein E (apoE) and exhibit increased amyloid load. To test whether excess ABCA1 protects from amyloid deposition, we crossed APP/PS1 mice to ABCA1 bacterial artificial chromosome (BAC ...
Veronica Hirsch-Reinshagen +9 more
doaj +1 more source
Molecular characterization of the ATPase component of a putative ABC type transporter in moraxella catarrhalis [PDF]
Cataloged from PDF version of article.Moraxella catarrhalis is one of the major causes of respiratory tract and middle ear infections. Little is known about the pathogenesis of M. catarrhalis infection.
Şahin, Jale
core
Characterization of Oligomeric Human ATP Binding Cassette Transporter A1 [PDF]
Maxime Denis +5 more
openaire +1 more source
FXR-mediated down-regulation of CYP7A1 dominates LXRα in long-term cholesterol-fed NZW rabbits
We investigated how cholesterol feeding regulates cholesterol 7α-hydroxylase (CYP7A1) via the nuclear receptors farnesoid X receptor (FXR) and liver X receptor α (LXRα) in New Zealand white rabbits.
Guorong Xu +14 more
doaj +1 more source
Impact of Methyl-β-Cyclodextrin and Apolipoprotein A-I on The Expression of ATP-Binding Cassette Transporter A1 and Cholesterol Depletion in C57BL/6 Mice Astrocytes. [PDF]
Azizidoost SH +4 more
europepmc +1 more source
The role of the ABCA1 transporter and cholesterol efflux in familial hypoalphalipoproteinemia
Defects in the gene encoding for the ATP binding cassette (ABC) transporter A1 (ABCA1) were shown to be one of the genetic causes for familial hypoalphalipoproteinemia (FHA). We investigated the role of ABCA1-mediated cholesterol efflux in Dutch subjects
G. Kees Hovingh +6 more
doaj +1 more source
Delivery of human apolipoprotein (apo) E to liver by an [E1(-), E3(-), polymerase(-), pTP(-)] adenovirus vector containing a liver-specific promoter inhibits atherogenesis in immunocompetent apoE-deficient mice [PDF]
Recombinant adenovirus (rAd)-mediated apoE gene transfer to the liver of apoE(-/-) mice is anti-atherogenic. However, first generation rAd vectors were associated with immune clearance of transduced hepatocytes, while an improved [E1(-), E3(-) polymerase(
Amalfitano, A +4 more
core

