Results 101 to 110 of about 12,429 (225)

Photobiomodulation therapy promotes the ATP-binding cassette transporter A1-dependent cholesterol efflux in macrophage to ameliorate atherosclerosis. [PDF]

J Cell Mol Med, 2021
Yin Q, Chang H, Shen Q, Xing D.
europepmc   +1 more source

Identification of Sterol-independent Regulatory Elements in the Human ATP-binding Cassette Transporter A1 Promoter

, 2002
The ATP-binding cassette transporter A1 (ABCA1) shows a differentiation-, cAMP-, and sterol-dependent up-regulation in human monocytes. As part of an ongoing study, we investigated the proximal promoter regions that are highly conserved between the human
Kaminski, Wolfgang E., Danuta Kielar, Porsch-Özcürümez, Mustafa, Moehle, Christoph, Mustafa Porsch-Özcürümez, Elke Dittrich-Wengenroth, Probst, Mario, Susanne Heimerl, Wolfgang E. Kaminski, Langmann, Thomas, Mohammed Taher, Christoph Moehle, Borsukova, Hana, Thomas Langmann, Mario Probst, Taher, Mohammed, Schmitz, Gerd, Heimerl, Susanne, Dittrich-Wengenroth, Elke, Hana Borsukova, Gerd Schmitz, Kielar, Danuta   +21 more
core   +1 more source

ABCA1 promotes the efflux of bacterial LPS from macrophages and accelerates recovery from LPS-induced tolerance[S]

Journal of Lipid Research, 2010
Macrophages play important roles in both lipid metabolism and innate immunity. We show here that macrophage ATP-binding cassette transporter A1 (ABCA1), a transporter known for its ability to promote apolipoprotein-dependent cholesterol efflux, also ...
Patricia A. Thompson, Karine C. Gauthier, Alan W. Varley, Richard L. Kitchens   +3 more
doaj   +1 more source

A Common R219K Variant of ATP-Binding Cassette Transporter A1 Gene Alters Atherometabolic Traits in Pregnant Women With Gestational Diabetes Mellitus. [PDF]

Front Endocrinol (Lausanne), 2021
Tang F, Guan L, Liu X, Fan P, Zhou M, Wu Y, Liu R, Liu Y, Liu S, Li D, Bai H.   +10 more
europepmc   +1 more source

Lipid efflux in human and mouse macrophagic cells: evidence for differential regulation of phospholipid and cholesterol efflux

Journal of Lipid Research, 2005
ABCA1 is a critical regulator of lipid efflux from cells, which is highly regulated at the transcriptional and posttranslational levels. However, cells from different species and different tissues, and primary versus immortalized cells, show different ...
Robert S. Kiss, Jovana Maric, Yves L. Marcel   +2 more
doaj   +1 more source

MicroRNA-33-5p inhibits cholesterol efflux in vascular endothelial cells by regulating citrate synthase and ATP-binding cassette transporter A1. [PDF]

BMC Cardiovasc Disord, 2021
Xie Q, Peng J, Guo Y, Li F.
europepmc   +1 more source

Expression and localization of ATP binding cassette transporter A1 (ABCA1) in first trimester and term human placenta.

, 2010
ATP binding cassette transporter A1 (ABCA1) is a membrane transporter which performs cellular efflux of cholesterol and phospholipid. ABCA1's cholesterol transporting role in human placenta appears to be crucial for normal fetal development.
Ietta, F., Bhattacharjee, J., Bechi, N., GIACOMELLO, EMILIANA, Fava, A., BHATTACHARJEE, JAYONTA, IETTA, FRANCESCA, Romagnoli, R., BECHI, NICOLETTA, FAVA, ANTONIO, Giacomello, E., ROMAGNOLI, ROBERTA, RICCI, LUANA, Paulesu, L.   +13 more
core   +1 more source

Pharmacological inhibition of ABCA1 degradation increases HDL biogenesis and exhibits antiatherogenesis[S]

Journal of Lipid Research, 2009
Expression of ABCA1 is regulated by transcription of the gene and calpain-mediated proteolytic degradation, and inhibition ABCA1 degradation results in increased ABCA1 and HDL biogenesis in vitro.
Reijiro Arakawa, Maki Tsujita, Noriyuki Iwamoto, Chisato Ito-Ohsumi, Rui Lu, Chen-Ai Wu, Kenji Shimizu, Tomoji Aotsuka, Hashime Kanazawa, Sumiko Abe-Dohmae, Shinji Yokoyama   +10 more
doaj   +1 more source

Assessment of genetic polymorphism associated with ATP-binding cassette transporter A1 (ABCA1) gene and fluctuations in serum lipid profile levels in patients with coronary artery disease. [PDF]

Saudi Pharm J, 2021
Bogari NM, Babalghith AO, Bouazzaoui A, Aljohani A, Dannoun A, Elkhateeb O, Amin AA, Bogari MK, Mazhar AA, Porqueddu M, Khan IA.   +10 more
europepmc   +1 more source

Organoids: From Bench to Bedside Applications

MedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li, Rui Cao, Maochen Li, Zichao Tian, Huahao Fan, Bixia Hong, Xiaojuan Liu   +6 more
wiley   +1 more source