Results 91 to 100 of about 30,215 (258)
Polarization of Human Macrophages by Interleukin-4 Does Not Require ATP-Citrate Lyase
Frontiers in Immunology, 2018 Macrophages exposed to the Th2 cytokines interleukin (IL) IL-4 and IL-13 exhibit a distinct transcriptional response, commonly referred to as M2 polarization.
Dmitry Namgaladze +7 more
doaj +1 more source
Nature Communications, 2023 The molecular mechanisms connecting cellular metabolism with differentiation remain poorly understood. Here, we find that metabolic signals contribute to stem cell differentiation and germline homeostasis during Drosophila melanogaster spermatogenesis ...
Charlotte M. François +4 more
doaj +1 more source
Potential therapeutic use of the ketogenic diet in autism spectrum disorders. [PDF]
, 2014 The ketogenic diet (KGD) has been recognized as an effective treatment for individuals with glucose transporter 1 (GLUT1) and pyruvate dehydrogenase (PDH) deficiencies as well as with epilepsy.
Dueñas, Nadia +2 more
core +1 more source
Plastid Engineering for Photosynthesis‐Driven Synthesis of Hyaluronic Acid in Tobacco
Plant Biotechnology Journal, EarlyView.ABSTRACT Hyaluronic acid (HA) is a glycosaminoglycan composed of alternating units of N‐acetylglucosamine and glucuronic acid. High moisture retention, viscoelasticity and biocompatibility are unique features that make HA polymers attractive compounds for medical applications and aesthetic purposes.
Amanda Lopes +10 more
wiley +1 more source
ACLY is the novel signaling target of PIP2/PIP3 and Lyn in acute myeloid leukemia
Heliyon, 2020 A fundamental feature of tumor progression is reprogramming of metabolic pathways. ATP citrate lyase (ACLY) is a key metabolic enzyme that catalyzes the generation of Acetyl-CoA and is upregulated in cancer cells and required for their growth.
Johnvesly Basappa +12 more
doaj +1 more source
Electron transport phosphorylation in rumen butyrivibrios: unprecedented ATP yield for glucose fermentation to butyrate. [PDF]
, 2015 From a genomic analysis of rumen butyrivibrios (Butyrivibrio and Pseudobutyrivibrio sp.), we have re-evaluated the contribution of electron transport phosphorylation (ETP) to ATP formation in this group.
Firkins, Jeffrey L, Hackmann, Timothy J
core +2 more sources
Molecular biology of ATP citrate lyase
, 2020 The full length Arabidopsis ACL-A1 and ACL-B2 cDNAs have been expressed in E. coli. Western blot analysis of Arabidopsis extracts, probed with antiserum raised against these proteins, indicate that At.ACL-Al and At.ACL-B2 cDNAs code for proteins of 45 kDa and 65 kDa, respectively.
openaire +3 more sources
Plant Biotechnology Journal, EarlyView.ABSTRACT Base excision repair (BER) is a critical pathway for repairing damaged DNA bases in cells; however, the mechanisms of protein recruitment and interaction in this pathway remain largely unexplored in higher plants. In this study, we used ‘84K’ poplar (Populus alba × P.
Aoyu Ling +8 more
wiley +1 more source
ATP citrate lyase in human adipose tissue.
Journal of Nutritional Science and Vitaminology, 1981 ATP citrate lyase [EC. 4.1.3.8] activity in human adipose tissue was assayed. The activity was considerably higher in tissue from patients who had been supplied with nutrients only by intravenous injection than that from patients who had orally taken a meal and then fasted overnight.
M, Suzuki, H, Okuda
openaire +3 more sources
Plant, Cell &Environment, EarlyView.ABSTRACT Isoflavones, secondary metabolites with numerous health benefits, are predominantly found in legume seeds, especially soybean; however, their contents in domesticated soybean seeds are highly variable. Wild soybeans are known for higher seed isoflavone contents than cultivars. Here we used experimental and modelling approaches on wild soybean (
Carolina A. Contador +5 more
wiley +1 more source