Results 81 to 90 of about 30,215 (258)

Characterization of water and wildlife strains as a subgroup of Campylobacter jejuni using DNA microarrays.

open access: yes, 2013
Campylobacter jejuni is the leading cause of human bacterial gastroenteritis worldwide, but source attribution of the organism is difficult. Previously, DNA microarrays were used to investigate isolate source, which suggested a non-livestock source of ...
Altschul   +55 more
core   +1 more source

Reactivity and inhibitor potential of hydroxycitrate isomers with citrate synthase, citrate lyase, and ATP citrate lyase.

open access: yesJournal of Biological Chemistry, 1977
The four isomers of hydroxycitrate have been tested as substrates and inhibitors for citrate synthase, citrate lyase, and ATP citrate lyase. None of the isomers served as a substrate for citrate synthase and they were moderate to weak inhibitors of this reaction.
A C, Sullivan   +3 more
openaire   +2 more sources

Phosphorylation of ATP-Citrate Lyase by Nucleoside Diphosphate Kinase [PDF]

open access: yesJournal of Biological Chemistry, 1995
Rat liver nucleoside diphosphate kinase (NDPK) and PC12 cell cytosol were used to determine whether NDPK could function as a protein kinase. NDPK was phosphorylated on its catalytic histidine using [gamma-32P]ATP, and the phosphorylated NDPK separated from [gamma-32P]ATP. The addition of phosphorylated NDPK to dialyzed PC12 cell cytosol resulted in the
P D, Wagner, N D, Vu
openaire   +2 more sources

LCN2‐ACOD1 Signalling Affects the Post‐Injury Regeneration of Skeletal Muscle Through Mediating Ferroptosis

open access: yesCell Proliferation, EarlyView.
LCN2 mediates the suppression of C2C12 myoblast proliferation and myotube formation via erastin‐induced ferroptosis. Mechanistically, the LCN2‐ACOD1 axis regulates skeletal muscle growth via mitochondria‐associated ferroptosis, providing a theoretical basis for the prevention and therapy of muscle‐related diseases.
Xiaojing Hao   +12 more
wiley   +1 more source

Lipidome and metabolome analyses reveal metabolic alterations associated with MCF-7 apoptosis upon 4-hydroxytamoxifen treatment

open access: yesScientific Reports, 2023
4-hydroxytamoxifen (OHT) is an anti-cancer drug that induces apoptosis in breast cancer cells. Although changes in lipid levels and mitochondrial respiration have been observed in OHT-treated cells, the overall mechanisms underlying these metabolic ...
Kazuki Nishimoto   +8 more
doaj   +1 more source

ATP-citrate lyase kinase and cyclic AMP-dependent protein kinase phosphorylate different sites on ATP-citrate lyase.

open access: yesJournal of Biological Chemistry, 1981
ATP-citrate lyase was phosphorylated by highly purified cyclic AMP-independent protein kinase (ATP-citrate lyase kinase) or the catalytic subunit of cyclic AMP-dependent protein kinase. Each kinase phosphorylated ATP-citrate lyase equally but the combination of both kinases increased ATP-citrate lyase phosphorylation additively.
S, Ramakrishna   +2 more
openaire   +2 more sources

ATP Citrate Lyase Improves Mitochondrial Function in Skeletal Muscle [PDF]

open access: yesCell Metabolism, 2015
Mitochondrial dysfunction is associated with skeletal muscle pathology, including cachexia, sarcopenia, and the muscular dystrophies. ATP citrate lyase (ACL) is a cytosolic enzyme that catalyzes mitochondria-derived citrate into oxaloacetate and acetyl-CoA.
Das, Suman   +8 more
openaire   +2 more sources

The Zma‐miRNA319‐ZmMYB74 Module Regulates Maize Resistance to Stalk Rot Disease by Modulating Lignin Deposition

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Stalk rot, primarily caused by Fusarium graminearum (Fg) and Pythium inflatum (Pi), is a major maize disease responsible for significant yield losses. The molecular mechanisms governing defence against these pathogens remain poorly understood. To uncover key miRNAs and their regulatory genes, small RNA, degradome, and transcriptome sequencing ...
Yanyong Cao   +16 more
wiley   +1 more source

Intravenous infusions of glucose stimulate key lipogenic enzymes in adipose tissue of dairy cows in a dose-dependent manner [PDF]

open access: yes, 2013
The present study was investigated whether increasing amounts of glucose supply have a stimulatory effect on the mRNA abundance and activity of key lipogenic enzymes in adipose tissue of midlactation dairy cows.
Al-Trad, Bahaa   +6 more
core   +1 more source

OsPT4 Facilitates Selenomethionine Transport and Biosynthesis to Enhance Seed Accumulation in Rice: Molecular Mechanisms and Biotechnological Potential

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Selenium (Se) is a vital micronutrient for humans, with important functions for health and anti‐cancer properties. Organic Se shows higher antioxidant activity and much lower toxicity compared to inorganic Se, making it safer for use. Selenomethionine (SeMet) is one of the primary forms of organic Se.
Yang Yang   +11 more
wiley   +1 more source

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