Results 91 to 100 of about 615,643 (389)

Identification and Functional Analysis of V-ATPaseA and C Genes in Hyphantria cunea

open access: yesInsects
Vacuolar (H+)-ATPases (V-ATPases) are ATP-driven proton pumps that play multifaceted roles across various organisms. Despite their widespread significance, the functional implications of V-ATPase genes in Hyphantria cunea, an invasive forest pest with a ...
Xiaojie Wang   +5 more
doaj   +1 more source

Enhanced expression of vacuolar H+-ATPase subunit E in the roots is associated with the adaptation of Broussonetia papyrifera to salt stress. [PDF]

open access: yesPLoS ONE, 2012
Vacuolar H(+)-ATPase (V-H(+)-ATPase) may play a pivotal role in maintenance of ion homeostasis inside plant cells. In the present study, the expression of V-H(+)-ATPase genes was analyzed in the roots and leaves of a woody plant, Broussonetia papyrifera,
Min Zhang   +3 more
doaj   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

open access: yesAdvanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim   +3 more
wiley   +1 more source

MOM19, an import receptor for mitochondrial precursor proteins [PDF]

open access: yes, 1989
We have identified a 19 kd protein of the mitochondrial outer membrane (MOM19). Monospecific IgG and Fab fragments directed against MOM19 inhibit import of precursor proteins destined for the various mitochondrial subcompartments, including porin ...
Griffiths, Gareth   +4 more
core   +1 more source

Features of V‐ATPases that distinguish them from F‐ATPases [PDF]

open access: yesFEBS Letters, 2001
The general structure of F‐ and V‐ATPases is quite similar and they may share a common mechanism of action that involves mechanochemical energy transduction. Both holoenzymes are composed of catalytic sectors, F1 and V1 respectively, and membrane sectors, Fo and Vo respectively. Although we assume that a similar mechanism underlies ATP‐dependent proton
Hannah Nelson   +3 more
openaire   +3 more sources

The Regulation of Trace Metal Elements in Cancer Ferroptosis

open access: yesAdvanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang   +5 more
wiley   +1 more source

Regulation of cardiac remodeling by cardiac Na/K-ATPase isoforms

open access: yesFrontiers in Physiology, 2016
Cardiac remodeling occurs after cardiac pressure/volume overload or myocardial injury during the development of heart failure and is a determinant of heart failure. Preventing or reversing remodeling is a goal of heart failure therapy.
Lijun Catherine Liu   +2 more
doaj   +1 more source

Requirement of Zn to demonstrate HCO3-stimulated ATPase activity of rat small intestinal brush border. [PDF]

open access: yes, 1979
The existence of a membrane-bound HCO3-stimulated ATPase in intestinal mucosa is controversial. A crude brush border fraction of rat small intestinal homogenates contained HCO3-ATPase activity which was inhibited by preincubation with 3 mM EDTA. Alkaline
Chou, LY, Humphreys, MH, Kaysen, GA
core  

H2O2‐Generating Advanced Nanomaterials for Cancer Treatment

open access: yesAdvanced Functional Materials, EarlyView.
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie   +8 more
wiley   +1 more source

Na/K Pump and Beyond: Na/K-ATPase as a Modulator of Apoptosis and Autophagy

open access: yesMolecules, 2017
Lung cancer is a leading cause of global cancer deaths. Na/K-ATPase has been studied as a target for cancer treatment. Cardiotonic steroids (CS) trigger intracellular signalling upon binding to Na/K-ATPase. Normal lung and tumour cells frequently express
Cassiano Felippe Gonçalves-de-Albuquerque   +4 more
doaj   +1 more source

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