Results 131 to 140 of about 615,643 (389)

Na+/K+-ATPase: ion pump, signal transducer, or cytoprotective protein, and novel biological functions

open access: yesNeural Regeneration Research
Na+/K+-ATPase is a transmembrane protein that has important roles in the maintenance of electrochemical gradients across cell membranes by transporting three Na+ out of and two K+ into cells.
Songqiang Huang   +3 more
doaj   +1 more source

Spatiotemporal Regulation of STING Activity by Linear Ubiquitination Governs Antiviral Immunity

open access: yesAdvanced Science, EarlyView.
This study uncovers a spatiotemporal regulation of STING activity by linear ubiquitination in antiviral immunity. At the early stage of the infection, LUBAC promotes STING linear ubiquitination to drive its trafficking from the ER to the Golgi apparatus for activation.
Yong Zhang   +13 more
wiley   +1 more source

The Oligomeric State of the Plasma Membrane H+-ATPase from Kluyveromyces lactis

open access: yesMolecules, 2019
The plasma membrane H+-ATPase was purified from the yeast K. lactis. The oligomeric state of the H+-ATPase is not known. Size exclusion chromatography displayed two macromolecular assembly states (MASs) of different sizes for the solubilized enzyme. Blue
Yadira G. Ruiz-Granados   +2 more
doaj   +1 more source

Methods used in the structure determination of bovine mitochondrial F1 ATPase.

open access: yesActa Crystallographica Section D: Biological Crystallography, 1996
With a size of 372 kDa, the F(1) ATPase particle is the largest asymmetric structure solved to date. Isomorphous differences arising from reacting the crystals with methyl-mercury nitrate at two concentrations allowed the structure determination. Careful
J. Abrahams, A. Leslie
semanticscholar   +1 more source

Histochemistry of ATPases. [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 1990
D G Baskin, William L. Stahl
openaire   +2 more sources

Pinosylvin Inhibits Inflammatory and Osteoclastogenesis via NLRP3 Inflammasome

open access: yesAdvanced Science, EarlyView.
Pinosylvin blocks LPS and RANKL induced NEK7/NLRP3 interaction, inhibiting NLRP3 inflammasome oligomerization and assembly, reducing IL‐1β maturation and GSDMD cleavage, and improving the inflammatory microenvironment and abnormal osteoclastogenesis. Abstract Pro‐inflammatory cytokines such as TNF, IL‐1, and IL‐6 trigger aberrant osteoclastogenesis and
Wei Zhang   +13 more
wiley   +1 more source

Sodium or potassium efflux ATPase

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2010
The K(+) and Na(+) concentrations in living cells are strictly regulated at almost constant concentrations, high for K(+) and low for Na(+). Because these concentrations correspond to influx-efflux steady states, K(+) and Na(+) effluxes and the transporters involved play a central role in the physiology of cells, especially in environments with high Na(
Begoña Benito   +1 more
openaire   +3 more sources

The SlDOF9‐SlSWEET17 Module: a Switch for Controlling Sugar Distribution Between Nematode Induced Galls and Roots in Tomato

open access: yesAdvanced Science, EarlyView.
Root‐knot nematode (RKN) disease seriously affects the yield and quality of vegetable crops. SlDOF9‐SlSWEET17 model helps plants resist RKN infection during early stage by switching off the sugar transport capacity of other SlSWEET proteins that are hijacked by RKNs.
Xiaoyun Wang   +14 more
wiley   +1 more source

A thermodynamic framework for modelling membrane transporters

open access: yes, 2018
Membrane transporters contribute to the regulation of the internal environment of cells by translocating substrates across cell membranes. Like all physical systems, the behaviour of membrane transporters is constrained by the laws of thermodynamics ...
Crampin, Edmund J.   +4 more
core   +1 more source

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