Results 91 to 100 of about 10,287 (223)

Atractylodes lancea Rhizome Polysaccharide Alleviates MCD Diet-Induced NASH by Inhibiting the p53/mTOR Pathway

International Journal of Molecular Sciences
Nonalcoholic steatohepatitis (NASH) is a form of chronic liver disease that is characterized by liver inflammation and steatosis, with possible progression to fibrosis. Currently, no drugs have been approved for the treatment of NASH.
D. Pi, Zheng Liang, Maoxing Pan, Jianwei Zhen, Chuiyang Zheng, Jinyue Pan, Wen Fan, Qingliang Song, Qinhe Yang, Yupei Zhang   +9 more
semanticscholar   +1 more source

Atractylodes macrocephala Koidz. and Cuscuta chinensis Lam. extract relieves insulin resistance via PI3K/Akt signalling in diabetic Drosophila

Journal of Traditional and Complementary Medicine
Background and aim Type-2 diabetes mellitus (T2DM) is mainly characterized by insulin resistance (IR) induced by hyperglycaemia and insufficient insulin secretion.
Yinghong Li, Ye Xu, Biwei Zhang, Zhi-gang Wang, Leilei Ma, Longyu Sun, Xiuping Wang, Yimin Lin, Ji-an Li, Chenxi Wu   +9 more
semanticscholar   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Effects of Crude Extract of Glycyrrhiza Radix and Atractylodes macrocephala on Immune and Antioxidant Capacity of SPF White Leghorn Chickens in an Oxidative Stress Model

Antioxidants
The natural edible characteristics of Chinese herbs have led more and more people to study them as an alternative product to antibiotics. In this study, crude extracts of Glycyrrhiza radix and Atractylodes macrocephala (abbreviated as GRAM) with ...
Chaosheng Zhang, Shaolong Wang, Yunsheng Han, A. Zheng, Guohua Liu, K. Meng, Peilong Yang, Zhi-Min Chen   +7 more
semanticscholar   +1 more source

Atractylodes macrocephala Koidz Alleviates Symptoms in Zymosan-Induced Irritable Bowel Syndrome Mouse Model through TRPV1, NaV1.5, and NaV1.7 Channel Modulation

Nutrients
(1) Background: Irritable bowel syndrome (IBS) is a common disease in the gastrointestinal (GI) tract. Atractylodes macrocephala Koidz (AMK) is known as one of the traditional medicines that shows a good efficacy in the GI tract.
N. Choi, Woogyun Choi, Jong-Hwan Lee, Joon Park, Y. Kim, Raju Das, J. Woo, B. Kim   +7 more
semanticscholar   +1 more source

Polysaccharide extracted from Atractylodes macrocephala improves the spleen deficiency constipation in mice by regulating the gut microbiota to affect the 5‐HT synthesis

Neurogastroenterology and Motility
The traditional herbal medicine Atractylodes macrocephala Koidz. (A. macrocephala) is commonly utilized for alleviating symptoms associated with spleen deficiency, abdominal distension, diarrhea, and constipation.
Lei Chen, Xiangbing Chang, Chuntao Wu, Guofu Luo, Peifeng Zhang, Wei Tian   +5 more
semanticscholar   +1 more source

Polysaccharide of Atractylodes macrocephala Koidz alleviates LPS‐induced proliferation, differentiation inhibition and excessive apoptosis in chicken embryonic myogenic cells

Veterinary Medicine and Science
Background Lipopolysaccharide (LPS) can induce systemic inflammation and affect the growth and development of poultry. As a kind of traditional Chinese medicine, polysaccharide of Atractylodes macrocephala Koidz (PAMK) can effectively improve the growth ...
Mengsi Fu, Jinhui Wang, Dan-ning Xu, N. Cao, Wanyan Li, Fada Li, Zhiyuan Liu, Yong Li, Chenyu Zhu, Yunmao Huang, Xumeng Zhang   +10 more
semanticscholar   +1 more source

Atractylodes Lancea and Its Constituent, Atractylodin, Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease via AMPK Activation

Biomolecules & Therapeutics
Metabolic dysfunction-associated steatotic liver disease (MASLD), which encompasses a spectrum of conditions ranging from simple steatosis to hepatocellular carcinoma, is a growing global health concern associated with insulin resistance. Since there are
Ga Yeon Song, Sun Myoung Kim, S. Back, Seunghee Yang, Yoon Mee Yang   +4 more
semanticscholar   +1 more source

Ultrasound-Assisted Extraction of Atractylodes chinensis (DC.) Koidz. Polysaccharides and the Synergistic Antigastric Cancer Effect in Combination with Oxaliplatin

ACS Omega
Oxaliplatin (OXA) is recognized as a first-line drug for gastric cancer. However, low accumulation of the OXA in the target site and the development of drug resistance directly led to treatment failure.
Minjie Liang, Yayun Wu, Jimin Sun, Ya Zhao, Lijuan Liu, Ruizhi Zhao, Yan Wang   +6 more
semanticscholar   +1 more source

Research progress on pharmacological effects of Atractylodes macrocephala polysaccharide and its application in animal production

Siliao yanjiu
Atractylodes macrocephala is a bulk medicinal and edible herb, known for its effects of strengthening the spleen, replenishing Qi, eliminating dampness, and promoting diuresis.
WEN Xingxing, CHEN Siqi, ZHANG Zhaohui, WEN Guihui, LIU Hexiang, GE Lingrui   +5 more
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